Meetings international invites all the participants from all over the world to attend international conference on Mass spectrometry going to be held in Queen of the Adriatic, City of Bridges Venice, Italy during September 17-19, 2018
Mass spectrometry 2018 give the best platform to all the persons related to field of academic and industry for sharing their knowledge and idea. This conference covers all the fields related to mass spectrometry and its importance in day to day life. In this conference there will be many workshops seminars and technical sessions take place, which will catch attention of expertise persons, scholars, and also students to attend Mass spectrometry conference. It would be enrich our knowledge idea in understanding the requirements of academic are and global pharmaceutical industry.
The theme of this conference is “ Current emerging trends in Mass Spectrometry ” we bring together a unique international mix of large and medium pharmaceutical industry, medical and clinical research and leading universities and institutions. This is a perfect platform to share experience, foster collaborations across industry and academia and evaluate emerging innovations around the world.
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Mass Spectrometry Conference Highlights
Mass Spectrometry conference influence an attractive moment to meet people in the experimentation field and therefore it takes a pleasure in opening a doorway to encounter the ability in the field, young researchers and potential World-renowned speakers, the most recent approaches, tactics, and the current upgrade in the field of pharmaceuticals industries, research, genetics, applied chemistry,and food and food industries.
Session-1: Mass Spectrometry Fundaments
Mass spectrometry that that uses an instrument called a mass spectrometer helps in identifying the type and amount of chemicals present in a sample by measuring the mass-to-charge ratio and abundance of gas-phase ions. A mass spectrometry produce charged particles from chemical substance which to be analyzed. It use electric and magnetic field to measure the charged particles. Most mass spectrometers work with positive ions. The ionization source is responsible for converting analytic molecules into gas phase ions in vacuum. This has been made possible by the development of soft ionization techniques. Mass spectrometry procedure includes, ionizing the sample which may be solid, liquid, or gas by bombarding with electrons and then they are subjected to separate according to their mass to charge ratio in an electric field.
Session-2: Current approaches in mass spectrometry
Searching metabolites and their comparison in a biological sample allow the construction of certain biochemical pattern. The methodology behind mass spectrometry that is used for sample analysis makes it possible for identification of many metabolites. Some approaches towards mass spectrometry are Hybrid mass spectrometry, Tom probe tomography, structural proteomics and genomics, Nano scale and micro fluid separation, metabolomics and mass spectrometry in biomedical research, Protein phosphorylation and non-covalent interaction, emerging separation techniques etc.
Session-3: Applications of Mass Spectrometry
Mass spectrometry has a number of applications in different fields like chemistry, biology, physics, clinical medicine and even space exploration. Mass spectrometry has gained popularity in various fields with high specificity and being increasingly utilized in the clinical laboratory and also in different research settings. This is used in proteomics, clinical medicine, drug discovery, geologic research for petroleum, Cancer screening and diagnosis, in environmental analysis, pharmaceuticals, forensic science analysis.
Session-4: Chromatography and Mass Spectrometry
Gas chromatography, liquid chromatography, ion mobility are used in mass spectrometry. GC/MS is used for smaller and volatile molecules like alcohols, benzenes, aromatics, and simple molecules such as fatty acids, steroids, hormones. Many compounds are impossible to analyze with GC/MS so LC/MS used to analysis of samples which are difficult to analyze. LC/MS expands the effective analytical use of mass spectrometry to a much larger number of organic compounds. CE-MS is used to identify clinically useful body fluid metabolites. CE-MS has now been developed into a strong system complementary to LC-MS. IMS is being more widespread in last 50 years and has several utilities as stand-alone instrument and also used for the detection of atmospheric compounds, explosives, petrochemical reagents, chemical warfare agents, and airport scanner devices.
Session-5: Interpretation of Mass Spectrometry
Interpretation is useful for identifying the chemical formula, characteristic fragment patterns and possible fragment ions from the mass spectra and a plot of relative abundance against mass-to-charge ratio. The interpretation include-Selecting peak of the molecular ion, Examine spectrum for peak clusters of characteristic isotopic patterns, Testing peak candidate by searching for other peaks correspond to reasonable losses, Looking for characteristic low-mass fragment ions and Comparing spectrum to reference spectra. It includes determining molecular weight, Natural Isotopic Abundance Ratios, Halogen Isotope Clusters etc.
Session-6: Mass Spectrometry Software
In Mass spectrometry, software is used to determine, analysis, and represent the data. Proteomic software Peptide identification algorithms fall into two broad classes: database search and de novo search. Proteomic software have data base search algorithm, DE novo sequencing algorithm and Homology searching algorithm. Mass spectrometry has several open data formats. Software contains viewers and converters.
Session-7: Mass Spectrometry in Pharmaceuticals
Mass spectrometry plays key role in pharmaceutical industries which includes from the very early stages of drug discovery through to late-stage development and clinical trials. MS can reveal a compound’s toxicology and efficacy. It can be used to study a compound’s pharmacokinetics—its distribution in the body over time. MS shows increasing applications in disease-related research and Metabolomics-based MS and gas and liquid chromatography were used to analyze the phenotypes of four cancer cell lines—two from ovarian cancer and two from colon cancer.
Session-8: Mass Spectrometry in Genetics
Biochemical genetic testing utilizes instrumentation like HPLC, LCMSMS , and GCMS to know altered levels of amino acids, organic acids, total and free cartinines, and acylcarnitines. It also evaluates levels of metabolites in newborns, in patients with phenylketonuria, a variety of other inborn errors of metabolism. Mass Spectrometry Laboratory provides services with capabilities in methods of measuring masses of biologically relevant molecules by mass spectrometry utilizing a High Performance Liquid Chromatography Triple Quadrupole Mass Spectrometer.
Session-9: Mass Spectrometry in Proteomics
mass spectrometry-based proteomics as an crucial tool for cellular and molecular biology and also for the emerging field of biology which include study of protein–protein interactions via affinity-based isolations on a small and proteome-wide scale, description of the malaria parasite genome and proteome , mapping of numerous organelles, , and the generation of quantitative protein profiles from diverse species. Proteins in proteomics can be identified by mass spectrometry and current MS method can identify any protein in a known genome sequence. MS can analyze peptides rather than full length proteins.
Session-10: Mass Spectrometry Imaging
MS imaging determining the distribution of proteins, peptides, lipids, neurotransmitters, metabolites and drugs in neural tissue sections in situ. Molecule-specific imaging can be achieved by using various ionization techniques that are suitable to different applications. MS has an important analytical technique in neuroscience research. MS imaging that can be used to investigate the topographical organization and spatial distribution of numerous different molecular analytes on complex surfaces such as brain tissue sections and characterizing the chemical changes resulting diseases and also monitoring the progression of lipid oxidation in response to external stimuli.
Session-11: Mass Spectrometry in Toxicology
Toxicology correlates the quantitative and qualitative relationship between the poison and their behavioral effects. High resolution mass spectrometry is used in clinical and forensic toxicology and environmental toxicology, it include pharmaceuticals, drugs of abuse and toxins in the field of drug metabolism.
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Mass spectrometry experiment is a high-throughput experimental method that characterizes molecules by their mass-to-charge ratio. The MS is composed of sample preparation, molecular ionization, detection, and instrumentation analysis processes. MS is beneficial in that it is generally fast, requires a small amount of sample, and provides high accuracy measurements. If the foreline pump is not maintained, the oil may become so contaminated that the optimum pumping is no longer possible. Initially, gas transport and metabolism ballasting may clean the oil. If the oil has become discolored then it should be changed according to the pump manufacturers’ maintenance manual. When rotary pumps are used to pump away conflict resolution, the solvent can become dissolved in the oil causing an increase in backing line pressure.
Mass spectrometry market is studied with respect to two segments like technology and application. The technology is segmented into single quadruple, Fourier transform, gas chromatography, tandem LC/MS, time of flight and others. Mass Spectrometry has applications in pharmaceuticals, energy, government research, utilities, diagnostics and environmental, food & beverages, security & defense, and industrial chemicals fields. Tandem mass spectrometry is expected to show significant growth during the forecast period due to its considerable advances in new born screening and protein sequencing. Mass spectroscopy market is divided into North America, Europe, and Asia Pacific. North America has largest market share followed by Europe, Asia Pacific market is expected to show a profitable growth rate due to the increasing usage rates of mass spectrometry in pharmaceutical industries and in food testing processes. The global mass spectrometry market was valued at $4,598 million in 2016, and is estimated to reach at $7,922 million by 2023, registering a CAGR of 8.0% from 2017 to 2023.
Key market players for mass spectrometry market are Thermo Fisher Scientific, PerkinElmer, Inc., Agilent Technologies, Bruker Corporation, Waters Corporation, Bio-Rad Laboratories, Danaher Corporation, Shimadzu Corporation and others.
KEY MARKET SEGMENTS
KEY PLAYERS PROFILED