Zayed Military Hospital, United Arab Emirates
Hassa Al Zaabi , MD, MSc Nephrology Medicine , is a specialist nephrologist at Zayed Military Hospital, Abu Dhabi, UAE .Al Zaabi started her medical education in The Arabian Gulf University in the Kingdom of Bahrain. Following her undergraduate education , Al Zaabi continued her postgraduate training in nephrology at Zayed Military Hospital. During her postgraduate training , Alzaabi obtained a Masters degree in Nephrology Medicine from University of Sheffield after training for a year at Sheffield Kidney Institute in Sheffield , UK.
Al Zaabi also worked as a Deputy Medical Director at Zayed Military Hospital for over 3 years and Head of Nephrology for a year .
Currently, Al Zaabi is working at Zayed Military Hospital at the clinic and dialysis unit and also works at the Ministry of Defense as a Head of Delivery Management Section . Her interests are Chronic Kidney Disease and End Stage Renal Disease.
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. Symptoms vary in severity and age of onset, but usually develop between the ages of 30 and 40.
ADPKD is a progressive disease and symptoms tend to get worse over time. The most common symptoms are kidney cysts, pain in the back and the sides and headaches. Other symptoms include liver and pancreatic cysts, urinary tract infections, abnormal heart valves, high blood pressure, kidney stones, and brain aneurysms.
ADPKD is most often caused by changes in the PKD1 and PKD2 genes, and less often by changes in the GANAB and DNAJB11 genes.It is inherited in a dominant pattern.
The diagnosis of ADPKD should be suspected in patients with clinical features mentioned and in those with a family history of ADPKD.
Preferred method — Mayo classification system, which categorizes patients into five prognostic classes from the lowest to the highest risk for disease progression (classes 1A, 1B, 1C, 1D, and 1E).
The Mayo classification requires demographic data such as the patient's age, height, and TKV.
The TKV can be calculated using a TKV calculator available online using a single representative coronal image .
Treatment for ADPKD involves managing the symptoms and slowing disease progression. The most serious complication of ADPKD is kidney disease and kidney failure. ADPKD is the most common inherited disorder of the kidneys. Tolvaptan is a vasopressin V2-receptor (V2R) antagonist with proven beneficial results in ADPKD.