To evaluate the feasibility of multiparameter quantitative measurement lung cancer by Gemstone Spectral Imaging (GSI) high-definition computed tomography. Seventy-seven patients who were found to have a lung mass or a nodule by CT plain scan for the first time received chest contrast CT scan with GSI mode on high-definition computed tomography. 

One of the mandatory components of radical treatment of patients with endometrial cancer is the impact on regional lymph nodes. Nowadays, pelvic lymphadenectomy remains not only therapeutic, but also a diagnostic method in case of predicting the effectiveness of treatment. However, it is important to point out that there are a lot of complications which can occur after dissection of lymph nodes. Lymphorrhea and lymphocele are among the most common postoperative complications of pelvic lymphadenectomy, with a reported incidence of 1% to 50%. Except for the occurrence of undesirable symptoms it can increase the time of drainage standing, which contributes to the delay of further stages of combined treatment. 

The present case study investigated a successful journey of a 49-year-old patient diagnosed with HIV and later on developed colorectal carcinoma that was treated and healed in a period of 4 years. Colorectal carcinoma refers to bowel cancer of the colon and rectum. According to Kenya health policy, cancers lead as the third cause of death in Kenya. According to Saidi et al, colorectal cancers account for 4050% of all cancers in the large bowel. Its incidence is amongst older people of 50 years and above. Agnes came as a stable patient, was enrolled into the HIV/TB clinic on 27/11/2012. Her CD4 at enrollment was 993 cell/ul. 

To explore the correlation between the expression level of vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC) tissue and quantitative parameters of spectral CT imaging. Forty-eight patients with NSCLC were subjected to a spectral CT imaging protocol before a surgical operation. The concentrations of iodine concentration, water concentration, and CT values at 40 keV in the region of interest were measured. The slopes of spectral attenuation curves (λHU) in the region were also calculated.

Titanium dioxide (TiO2) nanoparticles (NPs) can cause negative health effects such as respiratory tract cancer in rats. However, mechanisms involved in TiO2 NP-induced carcinogenicity have not been clearly defined and are yet poorly studied in vivo. The present study compared genotoxicity (DNA lesions with the comet assay and chromosomal damages with the micronucleus assay), oxidative stress (glutathione content) and inflammation (LBA numeration and cytokines) in rats exposed to 2 TiO2 NPs (NM105: P25, 23 nm, 85% anatase / 15% rutile, 46 m²/g; and NM101: Hombikat UV100, 7 nm, anatase, 300 m²/g) in 3 instillations at a 4-days interval accounting for total final doses of 0.5, 2.5 and 10 mg/ kg spread over 12 days. Endpoints were assessed at two time points, 2 hours and 35 days after the last instillation. This study confirmed two lung overload thresholds, previously described.

The global epidemic of obesity poses a serious health concern due to its association with chronic diseases, such as type 2 diabetes, cancer and cardiovascular diseases. These diseases are further associated with reduced quality of life and life expectancy, and contribute to high mortality rates. Obesity management primarily relies on pharmacotherapy to maintain a healthy body weight and prevent its progression to chronic diseases. However, the usefulness of anti-obesity drugs is limited due to poor efficacy, non-specificity and bystander effects. Therefore, novel approaches that could provide insights on obesity and obesity-associated diseases, as well as development of novel anti-obesity treatment modalities or improvement on the existing drugs are required. 

Pluronic (Tri–block copolymers) play an important role in pharmaceutical performance to increase the solubility and bioavailability of hydrophobic drugs. These micelles often lack stability, exhibit unsatisfactory drug loading capacity, or have broad size distribution this work aims to solve this issue by studying the solubilization of hydrophobic drugs in different pluronic micelles at variable temperature. Herein, a series of five pluronic micelles viz. P84, P85, F127, F108 and F68 have been select for study solubilization of hydrophobic drug Lamotrigine (LAM) at different temperatures i.e. 370C, 470C and 570C using UV-Visible spectroscopy. 

The AACCR is housed in the Radiotherapy Center at the Medical Faculty of Addis Ababa University Hospital, the only oncology referral center in the country. Data on newly diagnosed cancer cases are actively abstracted from medical charts of 22 major treatment or diagnostic facilities in the city. These data are entered and analyzed using CanReg5 program and Microsoft Excel. Rates were standardized to the 1960 World Standard Population