Kateryna Zupanets as a clinical pharmacist completed her PhD at the age of 27 years from National University of Pharmacy (Kharkiv, Ukraine) and last year she finished her post-doctoral studies at Clinical and Diagnostics Center of the National University of Pharmacy. She is the author of more than 50 papers in reputed journals (6 articles for SCOPUS journals). Dr. Zupanets has been working as a Co-Investigator in more than 50 trials of Bioequivalence studies and Phase I (Clinical and Diagnostics Center of the National University of Pharmacy).
In the epoch of antibiotic resistance and drug-dependent side effects the herbal drugs become more and more popular. According to the evidence level (EPOS 2012) herbal drugs hold Ib rate with the corresponding Grade A recommendation. The present parameters are the same as for Paracetamol. This fact is extremely reliable cause in terms of their potential herbal drugs can definitely be used to treat colds. As far as herbal medicines are as old as human kind they are well-studied and form the basis of modern pharmaceutics. Despite a huge variety of plant-based medicines and healing activities of natural substances they are still yielding surprising insights. For example, anti-inflammatory activity is not determined by one or other compound alone, it’s a result of correct composition. But it doesn’t mean that all herbal drugs with the similar content possess the same pharmacological activity. According to our in-depth studies of herbal medicine pharmacological activities we came up with an idea that there are no generics among herbal drugs. When studying a number of plant-based medicines such as novel dry extract BNO 1011 (Sinupret® extract), BNO 1045 (Canephron® N), micronized purified flavonoid fraction (Detralex®), significant biopharmaceutical differences were found in comparison with their copies, more precisely with phytosimilars. Although different manufactures can copy the ingredients and doses of raw material of well-known brands but it doesn’t maintain the same safety and efficacy. We have found out that phytoneering herbal drugs prove to be as effective as standard therapy due to the unique high-tech approach. Thus, standardized herbal drugs with scientifically determined efficacy are setting new reliable benchmarks which may help to treat diseases in a targeted and effective fashion.
Dr. Choi has worked with great enthusiasm and endeavor for developing functional foods or pharmaceutical ingredients from animal and plant resources and commercializing them. Currently, He is interested in developing the system inferring functional properties of natural extracts (Bio-FINE). The system is based on bio-information that can be extracted by comparing differently expressing genes between normal and natural extracts fed animals. Through the system, various functional properties of single as well as combinatorial natural extracts can be ranked and further utilized for commercialization.
Although luteolin is known to have potent anti-inflammatory activities, much less information has been provided on such activities of its hepatic metabolites. Luteolin was subjected to hepatic metabolism in HepG2 cells either without or with catechol O-methyl transferase (COMT) inhibitor. To identify hepatic metabolites of luteolin without (LMs) or with COMT inhibitor (LMs+CI), metabolites were treated by ß-glucuronidase and sulfatase, and found that they were composed of glucuronide and sulfate conjugates of diosmetin in LMs or these conjugates of luteolin in LMs+CI. LMs and LMs+CI were examined for their anti-inflammatory activities on LPS stimulated Raw 264.7 cells. Expression of iNOS and production of nitric oxide and pro-inflammatory cytokines such as TNF-α, IL-1ß and IL-6 were suppressed more effectively by the treatment with LMs+CI than LMs. Our data provide a new insight on possible improvement in functional properties of luteolin on target cells by modifying their metabolic pathway in hepatocytes
Yuan Chen is a Principal Scientist in the Department of Drug Metabolism and Pharmacokinetics at Genentech. Yuan has nearly 20 years of experience in the drug metabolism and pharmacokinetics discipline working at Roche and Genentech. She has been DMPK project lead for many drug discovery and development projects, and contributed to many clinical candidate nomination and filing of IND to the regulatory authorities. Yuan’s current research focus is on physiologically-based pharmacokinetic (PBPK) modeling for the prediction of human PK, absorption, and CYP-and transporter-mediated drug-drug interactions. She leads PBPK effort at Genentech and has been active member on IQ PBPK expert working groups.
Pirfenidone is the first treatment approved to treat Idiopathic Pulmonary Fibrosis (IPF). Film-coated tablets were developed to offer an alternative to the marketed capsule formulation, and the bioequivalence (BE) study of pirfenidone after single-dose of tablet and capsules under fasted and fed states were assessed. A physiologically-based pharmacokinetic (PBPK) model was developed to describe pharmacokinetic (PK) for pirfenidone under fasted and fed conditions. The mechanistic absorption model simulation captured the observed BE study data and explained the phenomenon of Cmax slightly exceeding the BE criteria based on the hypothesis of slower disintegration with capsule under fed condition. The PBPK simulation result further supports the conclusion that the small difference in Cmax between the tablet and the capsules observed in the fed state is not expected to have clinically meaningful impact on the benefit-risk profile of pirfenidone.
Bjorn Margeirsson is a mechanical engineer holding an MSc degree from Chalmers University of Technology in Gothenburg, Sweden and a PhD from University of Iceland since 2012. He serves as Assistant Professor at the University of Iceland since 2016 and Research Manager at the plastic manufacturers RPC-Saeplast and RPC-Tempra in Iceland since 2013. He has been involved in research, development and teaching within the field of heat transfer modelling, fresh fish processing, packaging and transport for 10 years.
Discussion about the environmental impact of single use plastic packaging has increased during recent years. Due to its high insulation value and strength to weight ratio, expanded polystyrene (EPS) boxes are the industry standard for packing fresh fish and the recommended choice worldwide, especially in case of poor temperature control during distribution. EPS boxes are available in different size ranges but the most common ones are designed for 3 to 25 kg of fish. For packing fresh, whole salmon, typically 20-22 kg of fish is packed with 4-5 kg of ice or ice packs on top in an EPS box with volume capacity of around 40 L and weight of around 650-900 g. The aim of the project Lighter salmon box is to integrate the methods of computational heat transfer modelling, structural analysis and laboratory experiments and in the real supply chain in order to improve the design of expanded polystyrene boxes used for export of fresh, farmed fish. The effects of decreased EPS density on strength and insulation are also studied. The cooperative partners are University of Iceland, the largest fresh fish box manufacturer in Iceland, Tempra ltd., and the largest farmed fish exporter in Iceland, Arnarlax ltd. The higher order objective is to decrease the environmental impact of fresh fish packaging.
Elena Horska research activities are focused on food marketing and internationalization, intercultural studies in consumer behavior, food trend perception and changes in market environment. The workshop is supported by principal investigators of research project of the Slovak Research and Development Agency Nr. APVV-16-0244.
The increase of milk and cheeses consumption belongs to the key problems of food and nutrition policy worldwide, because the consumption of these products has the irreplaceable health benefit. The main aim of the workshop is to discuss the possibility of increasing the consumption of milk and cheeses with special attention paid to the consumers in order to find products which are for them in every way satisfactory in the market. To increase consumption and popularity of milk and milk products we have to know and understand socio-economic and qualitative factors affecting the production and consumption of milk and cheese. There is a place to discuss microbiological and sensory aspects of milk quality as well as all external product and marketing features. Experiences from using various research techniques will be discussed and compared to in order to show how they contribute to discovering rational and emotional feelings and reactions of consumer, all together leading to understanding purchasing and consumer behaviour on milk and milk products market. Partial attention will be devoted to intercultural studies and perception of symbols as external product features.
Dr. Yahdiana Harahap is a Professor in the field of Pharmaceutical Chemistry especially Bioanaysis related to bioequivalence study and DNA Adduct. She received her Master Degree in 1994 and Doctoral degree in 2003 from Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Institute Teknologi Bandung. She has been The Head of Bioavailability-Bioequivalence Laboratory Faculty of Pharmacy Universitas Indonesia since 2008. She serves as member of Expert Council Indonesian Pharmacist Association, reviewer in several international journals, President elected on Asian Federation of Pharmaceutical Science, Head of Sub Collegium Indonesia Pharmaceutical Industry and as The Head of Pharmacy Division in Indonesian Accreditation Agency for Higher Education in Health (LAM PT-Kes). She has generated more than 80 scientific works published in international and national journals, thus presented them in national and international conferences.
Statement of the problem: Memantine hydrochloride is an N-Methyl-D-aspartate (NMDA) receptor antagonist and approved for treatment of moderate to severe Alzheimer’s disease. It is compulsory for the generic product of memantine hydrochloride to conduct the bioequivalence study. Bioequivalence studies are important to compare the systemic exposure profile of a test product to that of a reference product. This study was performed to investigate the pharmacokinetics and bioavailability of two memantine hydrochloride film coated tablet formulations in order to prove bioequivalence between the two formulations.
Methods: The study was a single dose, open label, randomized, two way cross over in 19 healthy subjects under fasting condition. The wash out period was five weeks. Blood samples were obtained prior to dosing and at 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 16, 24, 36, 48 and 72 hours after drug administration. Plasma concentration of memantine HCl was monitored using liquid chromatography tandem mass spectrometry. The pharmacokinetics parameter AUC 0-24 h and Cmax were tested for bioequivalence after log transformation of data and ratios of Tmax were evaluated non parametrically. Result: the point estimates and 90% confidence interval for AUC 0-72 h and Cmax were 97.43 to 104.13% and 97.15 to 105.96% respectively. Conclusion: The results indicate that two formulations of memantine HCl were bioequivalent thus may be prescribed interchangeably.
Viktoriia Propisnova graduated in Pharmacy from Kharkov Institute of Pharmacy (Ukraine) in 1992 and completed her PhD in 1999. She is the Associate Professor of the Department of Clinical Pharmacology and Clinical Pharmacy of the National University of Pharmacy (Ukraine). The main area of her scientific activity is the development and practical implementation of ideas and fundamentals of pharmaceutical care in applied medicine and pharmacy.
In Ukraine, the choice of OTC-drug in case of relief of particular non-dangerous symptoms is regulated by the Order of the Ministry of Health No. 283 "About approval of the list of medicines permitted for use in Ukraine, which are dispensed without prescriptions from pharmacies and their structural units" and Order No. 875 "About approval of the Standards for the pharmacist ". However, there are only lists of recommended medicines, without any indications of their interchangeability and quality in the both documents. In this issue a reference book "Rx-index: a guide to the equivalence of medicines" is a good argument to Ukrainian pharmacists. The authors describe the characteristics of medicines from the point of view of the therapeutic (bio-) equivalence code. Information about the drugs, registered in Ukraine at the time of publication, according to the ATC classification, complete list of analogues with the indication of the manufacturer, dose and dosage forms, main indications and contraindications, information about the therapeutic equivalence, short and sufficient information for the prescribing are presented in this book. For a generic replacement, the pharmacist is recommended to choose preparations having the same composition, the same dosage form and code A (products, registered on the base of full dossier, including innovative medicines), B (products, the effectiveness of which was proved by bioequivalence research) or B1 (products, the equivalence of which is not subject to proof or proved by the dissolution test (biowaver). Thus, in Ukraine today there is a source of reliable information about the quality of the studies performed during the registration of drugs, which will help any pharmacist to perform correct generic replacement or qualitative pharmaceutical care.
Dr Khorasani is Assistant Professor in the Department of Food Science and Technology, Shahid-Bahonar University, Kerman, Iran. She is interested in research and development in the field of Clinical Pharmacology, Food Processing and Food Nanotechnology. She has been supervising scientific projects on the Post Harvest of different agricultural products using herbal and plant-derived compounds. She has several years of teaching and lecturing experience as well as supervision of postgraduate research students
Millet is a general word used to refer to a wide range of small-seeded annual grasses, which have been grown for thousands of years in different parts of the world. They are still the main source of food and nutrition in some countries in Africa and Asia. Millet seeds are rich in oil and contain essential fatty acids and essential amino acids as well as a number of minerals. We have been formulating nanocarrier systems employing proso millet protein and different tocopherol homologues for the nanoencapsulation of hydrophobic compounds. These formulations possess added nutritional value, are cost-effective and are able to increase the bioavailability of the encapsulated material. Proso millet protein was extracted by either wet milling or ethanol and then used as the wall material together with tocopherol homologues to encapsulate curcumin and omega fatty acids. The formulated nanocarrier systems depicted spherical morphologies and had diameters in the range of 180–240nm and polydispersity index (PdI) around 0.2–0.3. The entrapment efficiency for omega fatty acids ranged from 47.5% to 68.5% and for curcumin ranged from 34.0% to 56.5%. It was observed that millet protein extracted by ethanol exhibited better performance than that extracted by the wet milling process. The encapsulated omega fatty acids and curcumin exhibited a lower degradation rate than corresponding free compounds at 60°C. The encapsulation showed no negative effect on the antioxidant activity of curcumin as assessed by the DPPH and ABTS assays. In conclusion, results of the present study suggest that the composite nanocarrier systems formulated using millet protein and different tocopherol homologues have great potential for the nanoencapsulation of lipophilic compounds and can increase the bioavailability of food compounds significantly
Pawan Saharan is currently employed at Biomix Network in the position of Chief Executive Officer and Chairman.
Swine flu HIV/AIDS common cold hepatitis a, b & c herpes simplex i&ii acute & chronic viral infections viral respiratory infections dengue fever human papilloma virus pharangitis (viral) sars rabies rota viral diarrhea allergies & asthma tuberculosis alzheimer benign prostate hyperplasia hepatic cellular carcinoma hypertension lupus (discoid and systemic) oral thrush autism premenstrual syndrome and endometriosis rheumatoid & osteo arthritis spinal muscular atrophy. This observation study reveals that after Radha108 Nano Peptide oral spray therapy, mean weight of study cases showed significant increase from baseline to end of treatment and these changes were observed in both the genders. Hence these results indicate that Radha108 Nano Peptide oral spray is very effective and safe among cases with indications like HIV, Swine flu, Allergy, Asthma, Arthritis, Diarrhea, Fever, Fatigue-Malaise, Anemia, Endometriosis etc. showing increase in weight gain as a parameter for overall wellness and improved quality of life, even in healthy population.
Somesh Sharma is an alumnus of Dr. Y.S.Parmar University of Horticulture and Forestry, Nauni Solan, HP India. He is currently working as Associate Professor in School of Bioengineering and Food Technology, Shoolini University. His chief interests lie in food processing, food fermentation, food industry waste utilization, Post-harvest management of horticultural crops for sustainable development of rural population residing in Western Himalayan region. Another important contribution and achievement is the development of complete technology for the utilization of persimmon fruits for production of functional beverage. During last seven years he has filled 11 patents related to development of various kinds of fruit and vegetable based products and waste utilization.
Fermentation is one of the oldest methods for the preservation of food. It has the advantage of being generally regarded as safe (GRAS) and offer immense opportunities for production of novel products which can be classified as “organic foods”, “natural foods”, “health foods”, “functional foods”, and foods for clinical nutrition. Production of food products such as wine, beer, bread, yogurt, cheese and pickle by fermentation constitutes most ancient technologies develop by man to improve the quality and storage life of food materials from time immemorial. The art of fermentation practiced by common man continue in spite of scientific and technology revolution but largely remained confined to rural or tribal areas due to high cost of inaccessibility of the industry made products in remote areas, taste of the people for the traditional fermented products and finally, there socio cultural linkages with such products. In western Himalayan regions the traditional fermented beverages form an important constituent of stable diet of the people. The traditional methods of preparing Indigenous beverages are simple and inexpensive. India has a rich knowledge of traditional fermented beverages prepared from milk (dahin, butter milk, lassi) and fruits. In North western Himalayan region especially Himachal Pradesh different traditional beverages are still being prepared and those include likarak/ghanti prepared using chulli, apple, pear etc., angoori, Lungri, and sur. Traditional starter cultures like Malera and Treh are used as starter culture inoculums in making these fermented beverages. However, in some of the products natural microflora is also used as a source of inoculum. Further, the ancient methods of making such foods are changing rapidly through modern microbiology. In recent years much interest has been generated in foods of Asian and African countries including India where such foods being manufactured according to the traditional but technologically less advanced methods at cottage scale by means of natural micro flora. So, in present review an attempt has been made to present the available information on different aspects of the traditional beverages. Marrying modern science with traditional food products is a vital necessity for the future of these nutritionally rich fermented food products.
Miroslava KaÄániová, research activities are focused on microbial analysis of food, effect of biologically active and natural compounds, focusing on the mechanisms of effects of these compounds on animal digestive system in vivo and in vitro, antimicrobial resistance of bacteria isolated from food, antimicrobial activity of natural compounds on different types of microorganisms.
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has become a rapid tool for microbial identification of food and beverages. The aim of the study was to evaluate microbiological quality of raw cow milk produced in Slovakia. Additionally, 35 raw cow milk samples from the western and middle Slovak producers were collected (Banovce nad Bebravou, Liptovsky Mikulas, Cerveny Kamen, Vazec). Samples were collected in sterilized sample containers and brought to laboratory with icebox for microbiological investigation. Samples were kept in a refrigerator (4±1°C) until the testing began. The total count of bacteria, coliforms, enterococci, lactic acid bacteria and microscopic filamentous fungi were detected in raw cow milk samples. Total numbers of bacteria were cultured on Plate count agar at 37 °C for 24-48 h, aerobically; enterococci were cultured on Enterococcus selective agar at 37 °C for 24-48 h, aerobically; coliforms bacteria were cultured on Violet Red Bile lactose agar at 37 °C for 24-48 h. The LAB were cultured on MRS (Main Rogosa agar), MSE and APT agar at 30 °C, microaerophilic. The microscopic fungi and yeasts were cultured on Malt extract agar at 25 °C for 5 days, aerobically. Isolated strains (total 220) were subjected to identification by the MALDI-TOF MS profiling. Typical bacterial colonies were selected for identification with MALDI-TOF MS Biotyper. In group of lactic acid bacteria three genera were identified: Lactococcus and Leuconostoc. Lactobacillus spp. was the most abundant genus, which was found in 35, Leuconostoc in 20 and Lactococcus in 15 samples. Lactobacillus was mostly represented with Lactobacillus plantarum, L. garvieae and L. acidophilus. Another bacterial isolates included Gram-positive and Gram-negative Citrobacter youngae, Enterococcus faecalis, Escherichia coli, Ewingella americana, Klebsiella oxytoca, Lelliottia amnigena, Raoultella ornithinolytica and others. Our study shows that MALDI-TOF MS could serve as an important method for identifying microorganisms for dairy industry needs.
Aysu Tolun has received her BSc and MSc degrees from the department of Food Engineering at Ankara University in 2000 and 2005, respectively. She worked at quality control departments of several food industries for 10 years. Later on she worked at the Project Information and Support Unit of Ankara University for three years as an expert. She earned her PhD degree from Ankara University in 2016 with her thesis on microencapsulation of bioactive compounds. Zeynep Altintas is the head of Biosensors and Receptor Development Group at the Technical University of Berlin. She serves as an expert reviewer for EU and Wisconsin Groundwater Coordinating Council (USA) funded projects, in addition to acting as a reviewer for numerous important journals in her areas of expertise. She is also a member of Royal Society of Chemistry (RSC).
Fruit originated phenolic compounds have a high demand owing to their bioactive roles . Although the incorporation of these compounds into the food products are important, their sensitivity against physicochemical factors create a great challenge . The present study investigates microencapsulation of the phenolic compounds to provide a solution for this problem by improving their stability and protecting them against oxidation, light, moisture and temperature. The effects of spray drying conditions on microcapsules obtained from grape pomace extract were comprehensively investigated for the first time. The results achieved in the current work indicated that the use of maltodextrin and gum arabic together for encapsulation of phenolic compounds, which were extracted from grape pomace, have provided better results than that of using maltodextrin alone as a coating material. The most effective yield with better hygroscopicity, phenolic content and antioxidant activity was accomplished at an inlet temperature of 140â—¦C, using mixture of maltodextrin DE4-7: gum arabic in a ratio of 8:2 and a phenolic extract (core):coating material in a 1:1 ratio. Thus, winemaking by-products having little or no commercial value can be converted into the value added products that contain natural antioxidants (polyphenols) and they can be used instead of synthetic antioxidants, which may have harmful effects on human health . The microcapsules produced by utilizing these optimum conditions have the potential to able to add polyphenols as functional ingredients into a range of foods and also to improve their storage stability that have an immense impact in industry and health sector.
Somesh Sharma is an alumnus of Dr. Y. S. Parmar University of Horticulture and Forestry, HP, India. He is currently working as Associate Professor in School of Bioengineering and Food Technology, Shoolini University. His chief interests lie in food processing, food fermentation, food industry waste utilization, Post-harvest management of horticultural crops for sustainable development of rural population residing in Western Himalayan region. Another important contribution and achievement is the development of complete technology for the utilization of persimmon fruits for production of functional beverage. During last seven years he has filled 11 patents related to development of various kinds of fruit and vegetable based products and waste utilization.
Statement of the Problem: Fruit vinegar is a fermented beverage from at least one kind of fruit. These vinegars are a rich source of disease-fighting phytochemicals such as polyphenols, flavonoids and also contain citric, malic, lactic, succinic, fumaric and tartaric acid. All fruit vinegars primarily contain acetic acid as the main organic acid. Production of high quality fruit vinegar depends on some of the major factors such as the choice of raw materials and the method of acetification. Fruit vinegars are considered superior than the other vinegars in term of sensory and nutritional qualities. Hence, in the present investigations the wild apricot fruit from the western Himalayan region of India was selected as a raw material. The fruit collected were analysed for various physicochemical and phytochemical components and found rich in total phenols, carotenoids and antioxidants. Further, the alcoholic and acetic acid fermentation was optimized for the production of quality fruit vinegar from wild fruit. The alcoholic fermentation of the must was found best in treatment prepared with 14oB initial total soluble solids. Further, the vinegar was produced using submerged fermentation using an inoculum of Acetobacter aceti. Further, the prepared vinegar was matured similar to wine maturation. But instead of oak wood barrels the wood chips of different woods such as Quercus leucotrichophora, Bombax ceiba and Acacia spp. were tried for maturation. Since, in western Himalayan region felling of oak wood trees is banned, hence, the use of wood chips during aging of wine or vinegar can be one of the alternative.
Navam Hettiarachchy, an IFT Fellow, earned her Ph.D. in Biochemistry from the University of Hull, England. She was a faculty in Peradeniya Medical School, Sri Lanka. She was the Director of Food Science Program at North Dakota State University and now a University Professor in the Department of Food Science, University of Arkansas. In recognition of sustained excellence she has been highly recognized with numerous awards for her teaching, research, and service. She has 6 patents, 3 books edited or co-edited, 20 Book Chapters, and 155 journal articles and over 380 presentations and has been serving as an editorial board member of reputed journals.
The market for nutraceutical and functional beverage was $71.5 billion in 2016 globally, and is projected to be $105.5 billion by 2021. This market growth is escalating since consumers are concerned about their health and interested in non-GMO, natural ingredients, low-calorie, reduced sugar/sugar free, antioxidants and stress relief, energy and sports drinks. To meet this demand natural and specialty products, relaxation to counter energy, beverages with bioactive nutraceuticals using fruits and vegetables blends have evolved. Anticancer, anti-hypertensive, and antioxidative effects of bioactives in fruit juices, probiotic fruit and yogurt blends and tea are in demand. The power of protein, hydrolysates and peptides represents relatively untapped opportunity and is moving into mainstream sports and energy, and seniors markets. A pentapeptide derived from rice bran in spray-dried orange juice with consumer acceptability demonstrated anti-cancer activity against prostate cancer and has the potential to serve as a functional ingredient that offers health benefits. High-protein beverages using a hydrolysate from non-GM soybean with three flavors [Chai tea (C), tangerine (T), and mixed berries (MB)] were developed. Beverages T and MB received highest sensory scores and very stable at refrigerated storage. These beverages have the potential for commercial application. Furthermore, we are developing novel and creative nano-encapsulated probiotics with non-GM soybean protein hydrolysates for intestinal health and better delivery of probiotics. This innovative, novel high-protein with incorporated probiotics will help expanding this non-GMO line to new food segments. For successful beverage development, nutrition, nutraceutical and functional profile with health benefits and economy need consideration.
Filipe E. Antunes has his expertise on Polymer Chemistry. His research includes polymer-surfactant association, polymeric coatings, nano and microencapsulation, rheological control and gelation of polymeric systems. Most of his research is developed within multinational consortiums with worldwide companies. He is the project leader of COLLING (Colloids and Innovative Nanomaterials Group) at University of Coimbra, Portugal.
The way human beings feed themselves strongly influences their physical and emotional balance. Meat products are an excellent source of nutrients and are widely consumed around the world. However, these products are also susceptible to chemical and microbiological deterioration, which creates health risks. Consumption of contaminated food and water kills 1.8 million people annually. In addition, each person is wasting an average of 150kg of food per year, also due to lack of food conservation. Packaged meat products arrive at the consumer's house in good food safety conditions. However, food contamination is a serious concern at the post-opening stage of the package. It is thus urgent to create more advanced solutions of food preservation, which reduce the contamination and increase the shelf-life after the package is opened. This project addresses this problem. New systems were developed to promote longer shelf life through the incorporation of consumer safe edible coatings in the meat products. Furthermore, this coating prevents the use of the protective N2/CO2 atmosphere in the packaging, which leads to the reduction of the amount of plastic used in the packaging, yielding a better environmental impact. The various types of performed assays included: chemical, physical and microbiological tests to identify coatings with improved bacterial elimination, light scattering and rheology tests to identify the best suited coatings for spray application, and electron microscopy to compare the level of meat degradation with and without coating. Color, taste, texture and odor were continuously monitored throughout the project. After the laboratory tests, the best performance coatings were applied in semi-industrial environment. Based on the results of Cover-ED Project, meat products with a new generation of preservation will be available to consumers. The results of Cover-ED Project allowed the development of a new generation of preservation meat products soon available to the consumers.
Elena Horska research activities are focused on food marketing and internationalization, intercultural studies in consumer behavior, food trend perception and changes in market environment
The perception and following choice of food products depends on various factors including external ones. We studied potential packages of selected milk products (mainly cheeses) to find out possible associations that consumers have with these products with assumption that food packaging plays an important role in attracting consumers' attention and generating expectations in the consumer that in turn affect their product perception and buying behavior (Gelici-Zeko, Lutters, Klooster, Wejjzen). Our research sample consisted from modern versus classical graphical designs including designs related to historical features of agriculture, milk production, countryside, livestock or any other symbols associated with traditional way of farming on the land, showing very natural character of milk products. From our research we found out that consumers prefer traditional packages connected with Slovak customs and traditions to more modern packages. Packages with rural and traditional motives are strongly associated with farming, home production, high quality and great taste. We can assume that properly chosen motive of the packaging can significantly influence the consumer. Secondly, graphical design of the package can show additional functions of the milk products, e.g. dietetic character, nutrition and calcium contents, protein intake, made for kids and in such a way attract different group of consumers. Additionally, at the end of the paper we identify potential graphical features useful to support the attractiveness of the milk product in certain group of customers. Also we recommend the steps for further studies, including intercultural comparative studies, cultural grounding and transfer of know-how among different regions to support small and medium milk producers in penetrating at the milk market.
Mohd Abul Kalam Azad is performing as a Smallholding Cooperative Dairy Expert in Milk Vita, Bangladesh contributing huge IGA activities through entrepreneurship dev. towards low income generating mass people nation widely for two decades. He has completed his BSc A.H (Hons.), MS in Dairy Science Degree from Bangladesh Agricultural University and MBA in Marketing & International Business Degree from International Islamic University Chittogtong. Presently, he is servicing in Milk Vita as a Manager. Previously served in Inter Chain Project Consultant AB Sweden, NORAD, Central Bank of Bangladesh and other national and international donor organizations augmenting SME development / rural entrepreneurship development.
Milk Vita – the largest pioneering dairy cooperative venture in Bangladesh deals with about 350,000 lt./day liquid milk production , collection , processing and marketing with a diversified set of dairy products nation widely & relentlessly proving the myth of successful rural prosperity as a model of least developed countries. In Bangladesh year round ( January – December) rate of milk production took place as 9.97% ,10.01% , 9.20% , 8.59% , 8,17% , 8.37% , 7,27% , 6.50% , 6.46% , 6,86% , 8.73% and 9.88% respectively. In Bangladesh milk vita has successfully developed a cooperative milk production model like AMUL, India beyond existing traditional or informal systems as well as combating all sorts of identified challenges.. Milk Vita covers annual growth rate about 17% in raw liquid milk production for the whole nutrition thrust folk in hectic mode augmenting smart synchronization of year round milk production (6.09 MMT,i.e 43% of demand) , requirement (14.02 MMT) & deficit (7.93 MMT, i.e 57% of demand) ( 4 DLS :2014-2015 ) in Bangladesh .Dairying in Bangladesh is generally characterized by small scale, widely dispersed and unorganized milk animal holders ,low productivity, lack of assured year-round remunerative producer price for raw milk, inadequate basic infrastructure for provision of production inputs , services and above all lack of professional management practices. Nowadays, Tropical Asia stands as the largest milk producing region of the whole world & its efficiency as an integrated smallholder production system provides financial, health and social benefits to millions of rural dwellers. Dairying may therefore serve as a powerful instrument for the rural prosperity in the least developed countries. Devising a viable dairy development strategy for the rural smallholder calls for detailed analysis of strengths, weaknesses, opportunities and threats posed by the external environment. In Bangladesh milk production increases 5.98% per year where demand increase about 10% due to increase of purchasing capacity and food habit change of consumers. Therefore, the potential plenty requirements for dairy entrepreneurship development / business opportunities in Bangladesh awaits and it may be synchronized by the establishment of small scale dairy enterprises and processing plants through Milk Vita a lot providing appropriate national & international dairy policy and institutional support services forwarding rural prosperity overcoming identified challenges. In this paper the picture of successful cooperative dairying in Bangladesh through Milk Vita has been displayed accordingly.
Navam Hettiarachchy, an IFT Fellow, earned her Ph.D. in Biochemistry from the University of Hull, England. She was a faculty in Peradeniya Medical school, Sri Lanka. She was the Director of Food Science Program at North Dakota State University and now a University Professor in the Department of Food Science, University of Arkansas. In recognition of sustained excellence she has been highly recognized with numerous awards for her teaching, research, and service. She has 6 patents, 3 books edited or co-edited, 20 Book Chapters, and 155 journal articles and over 380 presentations and has been serving as an editorial board member of reputed journals.
Edamame (vegetable soybean), rich in nutrients and other nutraceutical substances, is a good source to produce healthy snack chips rich in protein, and low in carbohydrates. Innovative edamame chips were developed with desirable physical properties including colour/brownness index, water activity, moisture contents, texture and consumer sensory acceptability attributes and reported on a 9-point hedonic scale for flavor, texture, mouth-feel, after taste, and overall acceptance, and a 5-point “Just-About-Right” scale for willingness to buy from edamame flour as the main ingredient (over 80%). The processing conditions (baking powder level, baking temperature and time, and thickness) were optimized. Based on these conditions with some final adjustments snack chips were prepared from dried edamame flour in combination with 10% of dried vegetables (spinach, carrot) and or fruit (blackberry, blueberry, strawberry). The optimized conditions for edamame chips preparation were 1.0 mm thickness of the extruded edamame dough and 1.2% and 2.5% (based on the edamame flour weight) of salt and baking powder respectively, with the baking temperature and time of 171â°C and 12 min respectively. The optimized chips containing edamame, alone and in combination with fruits and vegetables were evaluated for the sensory study. The chips containing carrot-blueberry received the best ratings for flavor, mouth-feel, crispiness, after taste, and overall acceptance. These edamame chips with high protein (~36-39%), crunchy, and tasty that demonstrated overall acceptability by consumers can serve as an alternate enjoyable snack that can substitute calorie dense snacks.
Aysu Tolun has received her BSc and MSc degrees from the department of Food Engineering at Ankara University in 2000 and 2005, respectively. She worked at quality control departments of several food industries for 10 years. Later on she worked at the Project Information and Support Unit of Ankara University for three years as an expert. She earned her PhD degree from Ankara University in 2016 with her thesis on microencapsulation of bioactive compounds.
Polyphenols are natural antioxidants that promote human health by reducing the risk of cancer, boosting immune system, and showing anti-aging and anti-inflammatory properties. However, they can be easily affected by humidity, temperature, light, oxygen, and enzymatic activities. In this work, we aimed to prolong the storage stability of polyphenols obtained from grape pomace under the optimum microencapsulation conditions. A combination of different wall materials, namely maltodextrin (DE4-7 or DE17-20) and gum arabic, was used for spray drying-based microencapsulation. Two different core: coating material ratios (1:1 ve 1:2), three different maltodextrin (MD): gum arabic (GA) ratios (10:0, 8:2 ve 6:4), and four different inlet temperatures (120, 140, 160, 180°C) were studied. The microcapsules obtained under the optimal condition (8:2 ratio of maltodextrin: gum arabic at 140 °C inlet temperature) were stored at two different relative humidity (33% and 52%) during 75 days. The analyses of total phenolic content, antioxidant activity, and individual phenolic compounds were carried out every 15 days, and the most stable microcapsules were achieved with maltodextrin DE4-7 prepared by adding gum arabic to the wall material at the ratio of 8:2. The microcapsules obtained using maltodextrin DE4-7 have demonstrated much better protection and longer-term stability than that of maltodextrin DE17-20. This could be attributed to the longer chain structure of DE4-7 that enables to coat the core material with higher efficiency . Microcapsules were also comprehensively studied and characterized using scanning electron microscopy (SEM) and high performance liquid chromatography (HPLC) techniques.
Jacob Adegboyega KOLAWOLE has completed his PhD at the age of 38 years from the Ahmadu Bello University, Zaria and The Robert Gordon, University, Aberdeen, UK in 1996. He is the Dean, Faculty of Pharmaceutical Sciences, University of Jos and Consultant to West African Health Organization, on development of guidelines and training manuals for, Pharmaceutical Finished products; Pharmaceutical Raw Materials; Standard Operating Procedures for Laboratories; Bioavalability /Bioequivalent. He has more than 40 publications in international journals
Food-drug interaction is a consequence of physical, chemical or physiological relationship between a drug and food. Failure to identify and properly manage food-drug interaction can lead to serious consequences such as reduction in absorption of certain orally administered drugs thereby leading to failure of treatments. This study sort to explore the effect of green tea on Metformin uses both in-vitro dissolution test and in-silico docking interactions models. Dissolution test was carried out on Metformin alone and Metformin in the presence of green tea using the official dissolution medium, phosphate buffer pH 6.8 and sampling done at USP timing intervals. Docking studies was carried out by using 10 phenolic compounds and metformin in the active site of the AMPK crystal structure, 4ZHX.pdb. Metformin alone complied with the USP requirement of 70% drug release while Metformin release in the presence of green tea was less than 70% at 45minutes. Phenolic constituents of green tea; (-)-epigallocatechine, epicatechine, theanine and theophylline were seen to form complexes with metformin through covalent bonding in the active site of AMPK. This study was able to establish the interaction of green tea on metformin dissolution profile and possible binding interactions in the binding site of AMPK enzyme. It was therefore concluded that the presence of green tea in the dissolution media along with metformin caused a decrease in its dissolution profile due to complex formation and that the catechins and theanine constituents of green tea could possibly compete for binding site residues with metformin