Amirah Alnour has her expertise in evaluation and passion in improving the health and wellbeing.. She has built this path after years of experience in research, evaluation, teaching and administration both in hospital and education institutions. In addition to her specialization in oral pathology in Damascus university, she has finished her diploma in oral medicine in university of Saint Joseph in Beirut, Lebanon. Meanwhile, she is certified in medical education after finishing the master program.
Statement of the Problem: When confronted with non-infectious granulomatous inflammation from the oral cavity, as pathologists it is important to relay information to the clinician to ensure appropriate testing is performed to rule out various causes of OFG
Findings: Crohn disease should be considered if abnormalities in hemoglobin, serum iron, transferrin or ferritin, Vitamin B12/folate are identified. GI endoscopy to evaluate for bowel involvement may be considered. Abnormal erythrocyte sedimentation rate or C-reactive protein studies can be seen in Fig. 5 a Low power magnification of Crohn disease. There are numerous similarities to idiopathic orofacial granulomatosis including epithelial hyperplasia, stromal edema and loosely formed granulomas with mixed inflammation.
Conclusion & Significance: typical granuloma from the lip in a patient diagnosed with Crohn disease. The granuloma is composed of epithelioid histiocytes, multinucleated giant cells, plasma cells, lymphocytes, and occasionally eosinophils Although not always present, sarcoid granulomas can have lymphocytes along the periphery and within the granuloma. Elevated angiotensin-converting enzyme can be associated with sarcoidosis. Abnormal chest X-rays may indicate sarcoidosis or tuberculosis
Dr. Bayoumi Hamuda is working at Ã“buda University. He is the president of ICEEE, member of agriculture committee of Hungarian Academy of Sciences, etc. He is dealing with the microbiomes and environment interactions for increasing soil quality and saving the environment from pollutants Also, roles of waste management, agroproductivity and environmental impacts related to the application of organic wastes on: soil quality, monitorization of organic matter; measurements of soil microbial biomass, enzymatic activities; microbial composition and roles of engineered metal oxide nanoparticles in agroecosystem. He is interested in the roles of climatic changes on biosphere, public health and healthcare; bioengineering; probiotics, antibiotics, xenobiotics and human gut microbiomes.
Most studies are limited to listing the specific diseases in the target area and very few attempts to assess the possible consequences of changing the ecosystem. Climatic change is one of the most important global environmental problems, which potentially increase the transmission and widespread of causative agents and changes in infectious disease transmission that impacts on human health. Many disease-causing organisms are strongly influenced by climate change. For this reason. The impacts of climatic changes on human health are divided into two groups: direct impacts such as heat shock and increased mortality in a population and indirect effects. The effects have been detected worldwide; the degree and types of the effect are varied, depending on the hygiene, location of the respective countries, and socio-economic conditions. Variations in the incidences of vector-borne diseases are associated with extreme weather events. It is assumed that global warming might lead to an increase in infectious disease outbreaks. So, it predicts that climatic changes that accompany global increasing the temperature will change the transmission risk of many causative agents of many infectious diseases through worldwide. Clearly, the influence of climate change on disease is a complex process. It is recommended to improve the level of education of public health and city planning to reduce the incidence of infectious diseases. Accordingly, understanding of the impacts of climate change on human health is needed with much more studies and data being asked in detail about the impacts of climate change. We hope this information stimulates further research towards this goal.
Syeda Nur-E-Jannat graduated from Dhaka Medical College, the best medical college in Bangladesh. She started her carrier in medicine and completed fellowship in internal medicine from Bangladesh College of Physicians and Surgeons (BCPS), worked as medical officer in district health complex, as Junior consultant (Medicine) at Government Employee Hospital, Dhaka, She completed her specialization in gastroenterology from Bangabandhu Sheikh MujibÂ Medical University (BSMMU) at Dhaka. Now she is working as assistant professor, gastroenterolology at Dhaka Medical College She is involved in teaching of undergraduate and post graduate students at Dhaka Medical College and is working as co-guide of a number of thesis. She has a number of publications in the field of medicine and gastroenterology in national and international journals.
X-linked adrenoleukodystrophy (X-ALD) is a devastating genetic disease with three main phenotypes (childhood cerebral forms, adrenomyeloneuropathy(AMN) and Addison disease(AD). Tuberculosis is the commonest cause of AD in underdeveloped countries whereas autoimmune destruction accounts for 75-80% cases in developed countries. This is the first case report of X-AMN/ALD in two brothers in Bangladesh confirmed by raised very long chain fatty acid (VLCFA). Our index patient of 19 years presented with anorexia, weakness, vomiting, weight loss for three years with increased pigmentation in perioral skin, lips, tongue, mucus membrane, palmar creases, knuckles, reduced scalp hair(figure-1a-d), postural hypotension, low BMI, was found to have low basal Cortisol (9.00 am),Â ACTH >1250Â pg/ml (normal<46), was diagnosed with AD. After three months he developed progressive spastic paraparesis along with cognitive declination and behavioral abnormality. His only brother was normotensive, clinically asymptomatic at presentation had only increased pigmentation on tongue, palmar crease, scanty scalp hair(figure-1,2a-d) and extensor planter reflexes. He had high ACTH(>1250 pg/ml) with normal basal cortisol (9.00am). Plasma VLCFA analysis revealed significantly high C26:0 with abnormal ratio of C24:0/C22:0 and C26:0/C22:0 in both brothers, with normal level in mother(table-1). MRI (T2 & FLAIR) showed bilateral hyperintense basal ganglia in index patient(Figure2:3a-c). Electrophysiological studies of nerve (SEPs, VEPs, BAEPs, NCS, EMG) were normal in both. Both were given steroid replacement. After three years, index patient became bed bound with slurred speech, urinary urge incontinence and his asymptomatic brother developed spastic paraparesis with cognitive impairment. None had gonadal impairment. Follow up MRI revealed lesion in brainstem in both along with atrophy of thoracic segment of spinal cord in index patient(Figure2:4a-f) and cerebellum, internal capsule involvement in his brother(Figure3:5a-d). Both were of pure AMN variety but due to presence of cognitive impairment and behavioral abnormality they can be categorized as rare cerebral variety of AMN
Since 2018, she is a Clinical Trials Coordinater of the Acute Febrile Illnesses Clinical Research Group, being involved in ¨Randomized double blind clinical study dengue vaccine” management from the financial premises, regulatory aspects and actions in the field. PhD student in “REPLICK: Multicentre study on the natural history and physiopathology on chikungunya infection” and “Evaluation of the incidence of SARS-CoV-2 and COVID-19 infection in Brazil – AVISA”.
In 2014, she discover the Floral Therapy and be graduated with International Certification in Bach Healingherbs Florals - HEALING HERBS INTERNACIONAL (England) - working for over 6 years with Bach Flower Essences systems, California, Saint Germain, Arizona Desert, Bush Australian, Minas, Mata Atlantica e Daughters of Gaia. works dowsing for organic analysis of diseases and dysfunctions. As a clinical pharmacist, she acts on the main non-prescription drugs, herbal medicines, aromatherapy and vaccines. For to 9 (nine) long years, she was a coordinator by Quality management in immunobiological processes: vaccines and tests in Instituto Tecnológico de Imunobiológicos, Biomanguinhos - Fundação Oswaldo Cruz – Rio de Janeiro, Brazil
Responsible for the Water Monitoring Program, preparation of all procedures related to the validation and collection of water, preparation and review of flowcharts, descriptive memorials and as-built and executive plans of the Bio-Manguinhos programs, improvement of production processes based on Q8, Q9 and Q10 using the tools: risk analysis, mapping of production processes by PMBOK and BISAGE, production indicators, technical review of documentation for clinical studies and development of new products. Monitoring in international and national inspections of the main regulatory bodies