2nd Annual Epigenetics Congress

Epigenetics 2019

Theme: Future Revolution through Gene Expressions

2ndAnnual Epigenetics Conference 2019 will be held in Singapore during November 27-28, 2019. It will bring together international mixture of consultants like academicians, scientists, and business professionals, the general public, current and prospective young scientists to share information and ideas about the development of epigenetics-based research. Researchers and Professors to discuss research and innovation in the field of Epigenetic therapy, which is the use of drugs or other epigenome-influencing techniques to treat medical conditions. This Conference is designed to provide a perse and current education that will keep medical professionals up to date the latest methodologies, strategies, and the present update in the field of heritable changes in gene expression. Annual Epigenetics Conference 2019 gathering will centre on the most recent and energizing developments in every aspect of epigenetics events inquire about, which offers a one of a kind open door for agents over the globe to meet, organize, and see new logical advancements. The aim of organizing the Epigenetics  Conference is to provide exposure to technologies and to provide knowledge about research work going on epigenetics.


Session 1: Epigenetics

Epigenetics is the study of hereditary changes in gene function without involving alterations in the DNA sequence. It involves the changes in a chromosome that affects gene activity and functions. It can be affected by a few factors including age, the environment/lifestyle, and illness state. The definition of epigenetics requires these changes to be heritable, either in the progeny of cells or of organisms.

Gene expression will be controlled through the action of agent proteins that attach to silencer regions of the deoxyribonucleic acid.

Session 2: Cancer Epigenetics

Cancer epigenetics is the study of heritable changes to molecular processes that influence the flow of information between the DNA of cancer cells and their gene expression patterns. This includes comparative (tumour cell versus normal cell) investigation of nuclear organization, DNA methylation, histone modification and the consequences of genetic mutations in genes encoding epigenetic regulators. Gene transcription can be activated or inhibited by reversible modification of the gene; this modification is termed an epigenetic change. This account of epigenetics in cancer reviews the mechanisms and consequences of epigenetic changes in cancer cells and concludes with the implications of these changes for the diagnosis, prognosis, and treatment of cancer.

Session 3: Epigenetics Diseases

Genetic causes for human disorders. Diseases, like cancer, involve epigenetic changes; it appears cheap to do to counteract these modifications with epigenetic treatments. A growing subclass of disease-causing mutations involves changes in the epigenome or in the abundance and activity of proteins that regulate chromatin structure. The disease may be caused by direct changes in epigenetic marks, such as DNA methylation, commonly found to affect imprinted gene regulation. The discovery of UPD was the clinical entry point into disorders of genomic imprinting in humans. Whereas PWS and AS were the first genomic imprinting disorders to be studied, Beckwith–Weidman syndrome (BWS), pseudohypoparathyroidism (PHP), and Silver–Russell syndrome (SRS) expanded the list and introduced many intriguing questions about how epigenetic defects lead to the disease phenotype. Epigenetic mechanisms principally include Aberrant DNA methylation and histone acetylation has been linked to a number of age-related disorders including cancer, autoimmune disorders and others. Since epigenetic alterations are reversible, modifying epigenetic marks contributing to disease development may provide an approach to designing new therapies.

Session 4: Epigenetics Mechanism

With the increasing variety of options for the treatment of cancer, it is becoming essential that the choice of anticancer therapy, or optimal combination of therapies, is based not only on conventional clinical/pathological criteria but also on the molecular phenotype of the tumour. Many solid tumours are initially sensitive to chemotherapy, but the vast majority will recur or progress with the ultimate failure of conventional cytotoxic chemotherapy treatment. In general, novel experimental therapies are first examined for efficacy in patients that have failed standard treatments and whose tumours have acquired resistance to cytotoxic drugs. The pattern of gene expression of a tumour that no longer responds to conventional treatment will be very different from that of the tumour at presentation due to the selection of drug-resistant subpopulations. However, we know very little about the molecular characteristics of tumours after conventional treatment failure or the underlying mechanisms that drive the acquisition of drug resistance.

Session 5: Plant Epigenetics

Plants are masters of epigenetic regulation. All of the major epigenetic mechanisms known to occur in eukaryotes are used by plants, with the responsible pathways elaborated to a degree that is unsurpassed in other taxa. DNA methylation occurs in CG, CHG, and CHH sequence contexts in plant genomes, in patterns that reflect a balance between enzyme activities that install, maintain, or remove methylation. As in other eukaryotes, histone-modifying enzymes influence epigenetic states in plants and these enzymes are encoded by comparatively large gene families, allowing for diversified as well as overlapping functions. The prominence of epigenetic regulation in plants reflects their mode of development, lifestyle, and evolutionary history. Unlike growth in mammals, in which organ and tissue formation are largely specified during embryonic development, plants grow by continuously producing new organs from self-sustaining stem cell populations known as meristems. Consequently, postembryonic development in plants is a continuous process shaped by environmental influences resulting in a high degree of phenotypic plasticity. Because plants are unable to escape their surroundings, they are forced to cope with changeable and often unfavourable growth conditions.

Session 6: Biochemical Approaches of Epigenetics

Biochemical mechanisms of Epigenetics deoxyribonucleic acid methylation, recognition of alkyl CpG, DE methylation in mammals, simple protein modifications, non-coding RNAs, microRNAs, the impact of body organization, mechanisms of polycomb proteins. Biochemical approaches to review Epigenetics Analysis of tissue-specific deoxyribonucleic acid methylation, ways for assessing genome-wide deoxyribonucleic acid methylation, methylation of Lysine-9 of simple protein H3: role in heterochromatin modulation and tumorigenesis, body substance modifications distinguish genomic options and physical organization of the nucleus, assessing epigenetic data.

  • MicroRNAs
  • Combined Epigenetic Therapies
  • Epigenetic and Cytotoxic Therapies
  • DNA methylation
  • Post-translational histone modifications
  • Non-coding RNA

Session 7: Genetics & Epigenetics inheritance

Epigenetic inheritance is an unconventional finding. It goes against the idea that inheritance happens only through the DNA code that passes from parent to offspring. It means that a parent's experiences, in the form of epigenetic tags, can be passed down to future generations. Genetics usually thought of a field of biology deals with the study of genes, genetic variation & heredity in living organisms. Epigenetic inheritance is an unconventional finding. It implies that a parent experiences, within the type of epigenetic tags, is passed right down to future generations. It goes against the thought that inheritance happens solely through the deoxyribonucleic acid code that passes from parent to offspring. Genetic alteration of the epigenome thus contributes to the epigenetic method can cause purpose mutations and disable deoxyribonucleic acid repair functions.

Epigenetic parts of the psychoneurotic method are involved in an exceedingly few Central sensory system infections, containing neurodevelopmental issue of comprehension wherever intrusion in learning and memory square measure the essential clinical variation from the norm. Perception for the foremost half alludes to the psychological procedures as well as the obtain of learning and also the capability to fathom an equivalent. There square measure around eighty-sixes a billion neurons within the human mind, that square measure from sets of giant and tiny scale conjunction systems.

Session 9: Cyto-Epigenetic Approaches

Combining genetic science & epigenetic approaches in chronic cancer of the blood improves prognosis prediction for patients. Cytogenetic is outlined because the study of body structure, location and performance in cells. Modern genetic science approaches square measure modify to label the body location of any Cistron exploitation completely different coloured dots, examine cells from any kind of tissue (even tumour cells), establish cells that have lost or gained a particular body whether or not specific regions of chromosomes are lost or gained while not ever observing the chromosomes beneath a magnifier.

  • Cancer cytogenetic
  • Karyotyping
  • Fluorescent in situ hybridization
  • Cytotaxonomy
  • Molecular cytogenetics

Session 10: Epigenetic in Aging

Ageing can be defined as all the phenomena that mark the evolution of a living organism towards death. Over time, ageing is expressed by the occurrence of typical diseases such as cancer, type 2 diabetes, cardiovascular disorders and neurodegenerative diseases. These causes of ageing are the subject of numerous scientific publications, including the excellent article “The Hallmarks of Aging”, and the number of research projects on these mechanisms continues to increase. Epigenetic changes have a considerable range of impacts on the maturing procedure. Epigenetic in Aging: At completely different levels these epigenetic changes happen, as well as decreasing the amount of the middle histones, changes within the samples of simple protein post-translational alterations and deoxyribonucleic acid methylation, substitution of accepted histones with simple protein variations and changes the noncoding RNA articulation (amid each scheme maturing and replicative senescence).The reversible plan of epigenetic information provides energizing thanks to remedial intercession in maturing and age-related maladies, as well as growth.

Session 11: Animal Epigenetics

Animal models to study environmental epigenetics. Epigenetics provides a means of understanding how environmental factors might alter heritable changes in gene expression without changing the DNA sequence, and hence the origin, of some diseases that are not explained by conventional genetic mechanisms. Research into an epigenetic transgenerational gift is restricted in lightweight of the very fact that a major part of the work has focused on the immediate impacts of ecological accommodation to toxicants and supplements. Pesticides are the reason for having sensational transgenerational epigenetic consequences for a considerable lot of the creature models which influencing the sensory system, regenerative and endocrine frameworks, and notwithstanding causing malignancy.
Market Analysis:
The worldwide business sector of Epigenetics is segmented in light of products, research territories, and geology. Increasing demand from patients for personalized medicines will fuel the demand for genetic testing during the forthcoming years. Personalized medicine offers tailored medical treatment to patients based on their molecular basis. Various developed economies such as Europe undergo genetic testing for the detection of various genetic and rare diseases. Detection of diseases at an early stage facilitates early treatment and helps reduce the severity of diseases.
According to the WHO, almost 70% of deaths from cancer occur in low and middle-income countries, so they have the necessary data to drive cancer-related policies. Cancer rates could further increase by 50%, to 15 million new cases, by 2020, as per the World Cancer Report. The American Cancer Society estimated in 2016, that there were 1,685,210 new cancer cases and about 595,690 deaths due to cancer, in the United States.
Importance and Scope:
Technological advancement in genetic testing is expected to drive the genetic testing market during the coming years. The demand for genetic testing is increasing across the globe owing to the availability of new tests as well as advancement in the genetic testing techniques. A genetic test is a test performed to identify the presence of a particular gene/s with a particular sequence of the genome. The gene/s can be identified either directly through sequencing or indirectly through various methods. Genetic testing practices are rapidly increasing in rare disease diagnostics and for personalized medicines, which in turn, is fuelling the growth of this market.
Related Societies
European Societies
Clinical Epigenetics Society | The Epigenetics Society  | Association of Clinical Cytogeneticists | British Society for Human Genetics | Clinical Genetics Society | Clinical Molecular Genetics Society | Genetics Society | Human Genetics Commission | Austrian Society for Human Genetics | Belgian Society for Human Genetics | Czech Society of Medical Genetics | Danish Society of Medical Genetics | Dutch Association of Clinical Genetics | Finnish Society of Medical Genetics | French Society of Human Genetics |  European Society of Human Genetics | European Genetics Foundation | European Cytogeneticist Association | European Society of Gene Therapy | Clinical Molecular Genetics Society 
USA Societies
American Society of Human Genetics | National Society of Genetic Counselors | American College of Medical Genetics | American Board of Genetic Counseling | American Board of Medical Genetics | Nation Coalition for Health Education in Genetics | International Society of Nurses in Genetics | Council of Regional Networks | Association of Genetic Technologists | Genetic Society of America
Asian Societies
Australian Epigenetics Alliance | East Asian Union of Human Genetics Societies | Association of Chinese Geneticists in America | Hong Kong Society of Medical Genetics | Japan Society of Human Genetics | Genetics Society of Korea | Korean Society of Human Genetics | Genetics Society of Vietnam | Turkish Association of Medical Genetics | Japan Society of Gene Therapy | American Human Geneticists of Indian Subcontinent Origin
Target Audience/who should attend?
Genomic Students 
Genomics Researchers 
Genomics Faculty (Professors, Deans & Directors of Biology Universities and Institutes)
Genomics Scientists 
Genomics Colleges
Pharmacology Scientists
Genetics Associations and Societies 
Genetic Counsellors 
Bio pharmacists 
Training Institutes
Public wellbeing experts 


  • Epigenetics
  • Cancer Epigenetics
  • Epigenetic Diseases
  • Epigenetics Mechanism
  • Plant Epigenetics
  • Biochemical Approaches of Epigenetics
  • Genetics & Epigenetics inheritance
  • Human Cognition Epigenetics
  • Cyto-Epigenetic Approaches
  • Epigenetic in Aging
  • Animal Epigenetics