Vaccine R&D: International Vaccine Congress

Prague, Czech Republic   October 29-30, 2018


Vaccine R&D 2018

Theme: A Global discussion on Vaccine Research & Development

Vaccine R&D conference looks forward to welcoming all the participants across the world to attend “International Vaccine Congress-2018 during October 29-30, 2018 in Prague, Czech Republic. The conference highlights the theme “A Global discussion on Vaccine Research & Development".

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Topics Covered in the conference:

Vaccine Conference conveys upon a stage to share and talk about every one of the developments and potential advantages and constraints of immunizations and how to avert and control ailments. The get-together fuses Plenary addresses, keynote talks courses by famous identities from around the globe notwithstanding notice introduction or e-blurbs, youthful specialist sessions, symposiums, workshop and Exhibitions. It centers around the themes that incorporate the accompanying: Research on new Vaccines, Infectious ailments and Non Infectious Diseases, Cancer Vaccines, Veterinary Vaccines, Pregnancy and Neonatal Vaccines, Hepatitis Vaccines, HIV/AIDS Vaccines, DNA immunizations, Recombinant vector antibodies, Inactivated/Killed Vaccines, Human papillomavirus (HPV) Vaccine, antibodies - supply and appropriation – gauges, immunizations and related substances, Vaccines approval - fabricating process, approval of testing calculations, Vaccines approval considers, estimation of pharmaceuticals, variety - pharmaceutical item, VEN framework (Vital, Essential and Nonessential pharmaceuticals), venoms and neutralizing agents, viral inactivation and evacuation systems - plasma items, infection inactivation and expulsion - blood item wellbeing, Post Vaccination Era.

Why to attend???

Vaccine researchers and immunologists around the world are concerned about development and proper applications of Vaccine R&D; "International Vaccine Congress 2018" to be held in Prague, Czech Republic from October 29-30, 2018 is a best opportunity to reach the largest assemblage of participants from the Vaccine development community. Detailed presentations where participants can discuss the information, meet with current and previous scientists, make with new vaccines developments, and receive recognition of their names at this event. World-renowned speakers and the newest updates in Vaccines and immunization are hallmarks of this conference.

Target Audience:

·         Researchers & Scientists related to Vaccine R&D

·         Deans and Professors

·         Directors, CEOs, Presidents and Vice Presidents

·         University Faculty

·         Medical Schools/Colleges

·         Nursing Schools/Colleges

·         Associations and Societies related to Vaccine R&D

·         Vaccination Programme Organising Government and Non-government Organisations

·         Business Entrepreneurs

·         Medical Devices Manufacturing Companies

·         Vaccine Manufacturing Companies

·         Vaccine Developers and Investigators

·         Training Institutes

·         Vaccinology/Immunology Students.

Scientific Session:

·         Vaccine Research & Development

·         Vaccine and Types

·         Veterinary Vaccine

·         Vaccination during Pregnancy

·         Vaccination for Children

·         Cancer Vaccine

·         HIV and AIDS vaccine

·         HPV vaccine

·         Production and Effectiveness of vaccine

·         Immunology of Infectious diseases

·         Vaccines for unconventional diseases

·         Vaccines Experimentation

·         Poultry Vaccine

·         Vaccines against Drugs

Session 1: Vaccine Research & Development

Vaccine development put through a lengthy, rigorous process of scientific evaluation before licensed for general use but the process is time-consuming. The clinical trials in which vaccines are evaluated ensure that licensed vaccines are safe, effective, and appropriate to use. In the past years vaccine development did the unprecedented Ebola disease outbreak galvanized research and response, as we continue to search for solutions, we must review the lessons learned in order to overcome the current challenges. The current system for developing, testing, and regulating vaccines developed during the 20th century as the groups involved standardized their procedures and regulations. The Vaccine R&D conference discuss the topics related to vaccination and immunology.

Session 2: Vaccine and Types

Vaccines contain an active component i.e, an antigen which generates the protective immune response. These vaccines are of two types live or inactivated. Live, attenuated vaccines consists of ‘wild’ viruses or a bacterium that has been weakened in the lab so it can’t cause disease. Because a live, attenuated vaccine is a natural infection, these vaccines are “teachers” of the immune system.Whereas  Inactivated vaccines are created by wild viruses or bacteria that have been grown in a culture medium and inactivated before being included in a vaccine. Inactivated toxins for bacterial diseases cause illness; or merely segments of the pathogen this includes both subunit and conjugate vaccines.

Session 3: Veterinary Vaccine

The major aims of Vaccine Conference on veterinary vaccines are to enhance the health and welfare of animals. Vaccination of creatures are utilized both to keep their contracting sicknesses and to counteract transmission of illness to humans. Both creatures kept as pets and creatures raised as domesticated animals are routinely immunized to prevent infections transmitted from wild categories. In a few cases, wild populations might be inoculated. While it is the case of transmitted diseases and zoonotic diseases.These veterinary vaccines have an impact not only on animal health but also on human health through preventing animal-to-human transmission of infectious diseases. The constant relation between human and animals researchers will be of major importance for finding new technologies. There are several vaccines are available and research going on in development of several veterinary vaccines i.e. rabies, canine distemper, canine parvovirus, irresistible canine hepatitis, adenovirus-2, leptospirosis, brocatelle, canine Parainfluenza infection, and Lyme ailment, and others.

Session 4: Vaccination during Pregnancy

Vaccinating the mother before, during and after the pregnancy does not only protect the mother, it will also protect the baby’s health. A risk to a developing fetus from vaccination of the mother during pregnancy is theoretical. No evidence exists of risk to the fetus from vaccinating pregnant women with inactivated virus or bacterial vaccines or toxoids. Pregnant mothers should not take live vaccines, such as Hepatitis B vaccine, polio vaccine, rabies and rotavirus vaccine; because there's a slight chance these will harm the unborn baby. During pregnancy tetanus/diphtheria/pertussis (Tdap) is recommended, preferably between 27 and 36 weeks gestation, to protect baby from whooping cough.

Session 5: Vaccination for Children

Vaccination given to children is called childhood Immunization. There are several vaccines for infants, newborn and small child’s up to 6 years so nowadays vaccination for babies are mandatory until unless the child has special circumstances, such as a compromised immune system or a neurological disorder all these precautionary steps are explained briefly on Vaccine Conference. In the society, we can see most of the children are facing with some immune disorders. Epidemics of many preventable diseases could return without vaccines, resulting in increased and unnecessary disability, illness and death among children. That is why it’s important that children, especially infants and young children receive recommended immunizations on time.

Session 6: Cancer Vaccine

 Vaccines are stated to healthy people to help prevent infections, such as measles and chicken pox. These vaccines use weakened or killed germs like viruses or bacteria to start an immune response in the body. Most of the cancer vaccines work the same way, but they make the person’s immune system attack cancer cells. Cancer treatment vaccines are different from the vaccines that work opposed to viruses. These vaccines try to get the immune system to attack against cancer cells in the body. Some cancer therapy vaccines are made up of cancer cells and parts of cells, or pure antigens. Sometimes a patient’s own immune cells are detached and exposed to these substances in the lab to create the vaccine. Once the vaccine is ready, it is injected into the body to increase the immune response against cancer cells. Cancer vaccines cause the immune system to attack cells with one or more specific antigens.The immune system contains special cells for memory, it’s hoped that the vaccine might continue to work long after it’s given.

Session 7: HIV and AIDS vaccine

Vaccine for AIDS does not yet exist, but efforts to develop a vaccine against HIV is going on. At present there is no restorative HIV immunizations affirmed by FDA,the virus that causes AIDS, have been underway for many years. CD4 cells are a type of lymphocyte,these plays an important part of the immune system. HIV vaccine would play a powerful role in ensuring the end to the AIDS epidemic. The “therapeutic” vaccine would not stop infection, but it may prevent or delay illness in people who do become infected, and might also reduce the risk of transmitting the virus to other people. The idea behind all HIV vaccines is to encourage the human immune system to fight HIV and all discussed in Vaccine Meeting.

Session 8: HPV vaccine

The vaccine protects against the human papillomavirus (HPV).If the virus is long lasting in the organs it leads to some types of cancers. The United States FDA has approved HPV vaccine to prevent cervical, vaginal and vulvar cancer. Sexually transmitted HPV infections are common and asymptomatic, untreated cases in women are the main cause of cervical cancer. HPV vaccine is recommended for young women through age 26 and for young men through age 21. It is important to take HPV vaccine for teenagers, Vaccine congress gives a brief idea on HPV vaccine.

Session 9: Production and Effectiveness of vaccine

Vaccine Conference states that Vaccine production has several stages. The manufacturing process of the vaccine has these steps Inactivation, Purification, Formulation. First, the antigen itself is generated. Viruses are grown either on a single cell i.e. on chicken eggs. The microorganisms are grown in bioreactors. Likewise, a recombinant protein derived from the viruses or microorganism can be generated in yeast. After the antigen is generated it is isolated from the cell by inactivating the virus. Recombinant proteins need many operations concerning ultrafiltration and column chromatography to be purified, and preservatives allow using multidose vials as Aggregate vaccines are more difficult to broaden and bring.

Session 10: Immunology of Infectious diseases

Research in laboratories is primarily focused on infectious diseases recently in developing countries. Currently, immune-mediated and infectious disease includes HIV/AIDS, Tuberculosis, Malaria, Pneumonia, Enteric Diseases, and Autoimmune diseases. Infectious diseases are contagious diseases caused by pathogenic microorganisms. The basic pathogenic mechanisms  leading to the development of advanced diagnostic tools and  vaccines used in  prevention and control of infection and the identification of new targets for antiviral and anti-parasitic drugs. Pathogens inhibit functioning of cytokines mechanisms and arrest immune recognition of infected cells. Natural killer cells are important for eliminating cells infected by virus, and by anti-HIV immunity.

Session 11: Vaccines for unconventional diseases

Vaccination against infectious diseases are very common but now a days antibody-inducing vaccines are introduced which can direct against non-infectious diseases and some unconventional indications vaccines against cancer, allergy, autoimmune diseases. These vaccines are introduced far before. But still, in promising late stage with some exceptional failures, there is still no counteracting agent prompting immunization other than microorganism antigens i.e. focusing on self-antigens, enslavement atoms antigens and others. Several clinical trials might have given us a golden fruit soon on this research. Vaccines for unconventional diseases are explained briefly in Vaccine conference.

Session 12 : Vaccines Experimentation

All vaccination candidates must be put through an extended, exhaustive methodology of legitimate appraisal before they can be approved for general use. This technique is dreary – it can take up to 10 years just to move a confident vaccination through the three times of clinical progression alone. Nevertheless, it is furthermore basic. The clinical preliminaries in which antibodies are surveyed ensure that approved vaccines are shielded, great, and fitting for the masses bound to use them. IAVI investigators have broad inclusion in associated examine for counter acting agent plot, the elucidation of inoculation thoughts into testable things, and the appraisal of such vaccination rivals in starting period clinical preliminaries.

Session 13 : Poultry Vaccine

Vaccination has a fundamental impact in the prosperity organization of the poultry surge. There are different infections that are kept away from by vaccinating the flying animals against them. A vaccination keeps a particular ailment by enacting or boosting the winged creature's resistant structure to make vaccines that consequently fight the assaulting causal animals. A trademark interruption that truly causes the affliction will have an unclear result from the fowl will make antibodies that fights the present assault and furthermore to hinder future assaults by the same causal living things. Desolately flying animals that breeze up tainted by and large advance toward getting to be unthrifty, non-gainful or even fail horrendously. A pollution caused by trademark assault will be uncontrolled and in this way has the probability of causing genuine mischief; anyway vaccination gives a technique for controlling the result with inconsequential harm to the flying animals.

Session 14 : Vaccines against Drugs

Internationally, drug addiction is a serious issue. One treatment being considered is vaccines against medications of mishandle. The vaccines got against the medication can take up the medication and turn away it from achieving the reward focus in the cerebrum. Barely any such antibodies have entered clinical preliminaries, however explore is going on rapidly : Nicotine immunization, Morphine and heroin immunizations, Drug particles and insusceptible framework, Linkage science, adjuvants and immunological proteins, Cocaine immunizations.


Market Analysis:

International Conference on Vaccines and Immunization is the best stage where you can consider the novel techniques to prevent diseases and expanding insusceptibility levels. This conference had particularly done with the diverse themes like bacterial immunizations, viral vaccines, travel and palatable immunizations and so on and cardiovascular immunopathy, neurological and respiratory immunopathology and so forth with various sessions. Vaccine conference-2018 invites Young  researchers at each profession stage to submit abstracts and  announcing their  recent logical discoveries and research in immunization and vaccination in oral and publication sessions. The congress will incorporate welcomed speakers, oral introductions, notice session and the youthful researcher grant.
Scope and Importance:
Vaccinology and Immunology meeting unites the Global pioneers in Immunology and significant fields to introduce their examination at this elite logical program. The Vaccine Conference facilitating introductions from editors of conspicuous alluded diaries, prestigious and dynamic agents and leaders in the field of Immunology and vaccinology. Vaccination is a key to destroy the illnesses. It is a subject for the experts who looks past the clinical prospects. Vaccinology is a noteworthy field in destruction of ailments. Conventional ways to deal with antibody configuration were to inactivate the human pathogen or a related creature homologue, Vaccinology is the study of vaccine and how the safe framework reacts to immunizations, yet furthermore incorporates ceaseless assessment of vaccination projects and immunization wellbeing and viability, and observation of the study of disease transmission of immunization preventable illnesses. This part gives a concise review of a portion of the fundamental ideas of immunology and Vaccination.
Why Prague | Czech Republic:
The help of innovative work (R&D) is one of the Government's needs in the Czech Republic. The help of Vaccine R&D was at CZK(Czech Currency) 9.67 billion out of 1999 and has expanded to the current CZK 23 billion amid the most recent 10 years, which is an expansion of 238%. Estimated by the offer of GDP, we moved from 0.52% of every 1999 to 0.62% of every 2008, which is the normal accomplished by the EU-27. Notwithstanding this unquestionable positive pattern, the required for the development of the R&D standard and better utilization of its outcomes is apparent. The advantages for economy and society remain generally low in the Czech Republic. In some regard, it is a result of the present arrangement of R&D open help, which is somewhat decentralized. On a fundamental level, all Ministries and Central Administrative Authorities bolster R&D from their own financial plan.
Vaccine Markets in Eastern Europe to 2022:

The report bundle Vaccine Markets in Eastern Europe to 2022 offers the most progressive industry information on the real market circumstance and future viewpoint for antibodies in various Eastern European nations. The bundle incorporates nation reports from the accompanying nations: Armenia, Bosnia Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Estonia, Georgia, Greece, Hungary, Latvia, Lithuania, Macedonia, Moldova, Poland, Romania, Russia, Serbia, Slovakia, Slovenia, Turkey and Ukraine. The exploration incorporates authentic information from 2011 to 2017 and gauges until the point when 2022 which makes the reports a precious asset for industry administrators, promoting, deals and item chiefs, specialists, investigators, and other individuals searching for entering industry information in promptly available records with unmistakably exhibited tables and charts.
Market outlook of the global vaccine market:
The vaccine showcase is relied upon to achieve USD 49.27 Billion by 2022 from USD 34.30 Billion out of 2017, at a CAGR of 7.5%. The development of the market is ascribed to the rising pervasiveness of ailments, expanding government and nongovernment financing for vaccine advancement, and expanding ventures by organizations.

More up to date and more costly vaccines are coming into the market speedier than at any other time. Vaccine improvement: expanding speculation. Tripled in an incentive from USD 5B out of 2000 to nearly USD 24 B in 2013 – Influenza antibody showcase: assessed at $2.9 billion of every 2011 to $3.8 billion by 2018 – US: $1.6 billion of every 2011 to $2.2 billion out of 2018. The worldwide market anticipated ascending to USD 100 B by 2025. More than 120 new items in the advancement pipeline. Changing the status of the immunizations inside the pharmaceutical business. New plan of action for vaccines is rising.
The vaccines market is highly competitive with the presence of various players. Some of the major players operating in the market are GlaxoSmithKline, plc (U.K.), Pfizer, Inc. (U.S.), Merck & Co., Inc. (U.S.), Sanofi Pasteur SA (France), Astellas Pharma Inc. (Japan), CSL Limited (Australia), Emergent BioSolutions, Inc. (U.S.), Johnson & Johnson (U.S.), MedImmune, LLC (U.S.), Serum Institute of India Pvt. Ltd. (India), Bavarian Nordic (Denmark), Mitsubishi Tanabe Pharma Corporation (Japan), Daiichi Sankyo (Japan), Protein Sciences Corporation (U.S.), and Panacea Biotec (India).
Associations & Societies Associated with Vaccines :
• The Lancet Infectious Diseases
• European Respiratory Society (ERS)
• European Society for Paediatric Infectious Diseases (ESPID)
• Global Chinese Association of Clinical Microbiology and Infectious Diseases (GCACMID)
• Infectious Diseases Society of America (IDSA)
• International Society of Chemotherapy (ISC)
• Infectious Diseases Society of America
• International Society for Infectious Diseases (ISID)
• International Society of Chemotherapy, Infection and Cancer
• Federation of Immunological Societies of Asia-Oceania
• The International Society for Interferon and Cytokine Research, USA
• Federation of Clinical Immunology Societies, USA
• European Society of Gene Therapy, Germany
Universities associated with vaccines:

• University of Bath,UK
• American College Health Association (ACHA) Hanover, Maryland
•  The College of Physicians of Philadelphia,US
• Erasmus University Rotterdam,Netherland
• University of BERN,Swizerland.
• University of Cambridge
• University of Oxford
• The University of Sydney
• Johns Hopkins University
• Saba University School of Medicine, Netherlands
• University of Minho, Portugal
• Medical University of Lublin, Poland
Global Funding Bodies:
• United Nations Children’s Fund (UNICEF)
• Global Alliance for Vaccines and Immunization (GAVI)
• Rockefeller Foundation (RF)
• Centre for Disease Control and Prevention (CDC)
• Bill and Melinda Gates Foundation
• American Academy of Pediatrics (AAP)
• Vaccine Foundation (V Foundation)
• National Institute of Health(NIH)
• Children’s Vaccine Initiative (CVI)
• Center for Infectious Disease Research And Policy (CIDRAP).
  • Vaccines & Immunization
  • Human vaccines-Infectious & Non-infectious
  • Modern Technologies in Vaccine Discovery & Development
  • Vaccine Adjuvants & Delivery Technologies
  • Translational, Clinical Evaluation & Field Trials of Vaccines
  • Cancer Vaccines & Immunotherapy
  • Child vaccination & Immunization
  • Recombinant Vaccines
  • Travel Immunization
  • Vaccine safety & Efficacy
  • Vaccines Preclinical & Clinical Trials
  • Veterinary Vaccines
  • Influenza and Respiratory Vaccine
  • HIV/AIDS Vaccines
  • HPV & Hepatitis Vaccines
  • Malaria & TB Vaccines
  • Stem Cell Immunology
  • Ebola Vaccines
  • Vaccines for pregnant women
  • Bacterial Diseases & Viral Vaccines
  • Vaccines Industry & Manufacturing
  • Geriatric Immunization
  • Nipah virus vaccine

3 Organizing Committee Members

1 Renowned Speakers

Mohamed Samir

Zagazig University, Egypt

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