Webinar on

Pharmacology

June 24, 2021

Scientific Program

Keynote Session:

Oral Session 1:

  • Pharmacology | Pharmacokinetic and Pharmacodynamics | Pharmacogenetics and Pharmacogenomics | Immunopharmacology
Meetings International -  Conference Keynote Speaker Huang  Ling photo

Huang Ling

Medical Acupuncture And Pain Management Clinic, Brazil

Title: Why Homeopathy in Prevention and Treatment of SARS-Cov-2 Infection?

Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all chronic diseases in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Researcher in the University of São Paulo, in the Ophthalmology department from 2012 to 2013.Author of the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine. Author of more than 60 publications about treatment of variety of diseases rebalancing the internal energy using Hippocrates thoughts.

Abstract:

Introduction: SARS-CoV-2 is a virus that emerged in Wuhan China (December-2019). On February 2021, there was 113 millions cases confirmed cases and 2.5 millions deaths worldwide. In TCM, COVID 19 infection is classified as external pathogenic factor invasion. According to a previous study of the author, more than 97% of the 409 patients analyzed have chakras’ energies  deficiencies. Purpose: The purpose of this study is to demonstrate That the use of homeopathy medications to replenish the chakras’ energies centers are important to maintain the functioning of the internal massive organs, responsible for the production of Yin, Yang, Qi and Blood. Demonstrate how the lack of this energy in the majority of the patients studied could be leading to the complications associated with SARS-CoV-2 infection. Methods: A clinical case report of a 42-year-old male patient, layer and work on the military. He was diagnosed with chakras energy deficiencies in November of 2019, and was performing treatment for replenishment of the chakras energy with homeopthy medications. In May 2020, the patient returned, reported to have symptoms of redness on the face and neck, when he went to bathroom to check on the redness, he faintened for the period of five minutes. He was taken to the emergency, exams were performed and nothing was found.   He also reported shortness of breath. The patient had no cought and no fever. He received treatment based on the reasoning of Traditional Chinese Medicine, through the Five Elements theory. The shortness of breath was associated with deficiency of the Kidney or the second chakra. The previous measurement had shown deficiency in 7 of the 7 chakras. The patient was oriented to increase the water intake to improve the energy of the Kidney, and treatment was started with homeopathy medications, to replenish the energy of the chakras, according to the theory entitled Constitutional Homeopathy of the Five Elements based on Traditional Chinese Medicine, on concentration of 1000CH, as he had taken 30CH and 200CH of the homeopathy (Natrum Muriaticum, Phosphoros, Sulphur, Calcarea Carbonica, Silicia).  Medication for taking out Heat retention were also recommended (Mercurio solubilis 200CH and Aconitum 6CH) as well as Chinese dietary counseling. After, it was found that the patient had been in contact with three other people who have coronavirus infection and died from the complications.  Results: The patient presented great improvement of all symptoms, on the following day of the start of the medication, not needing hospitalization.  Conclusion:  When treating patients with chakras’ energies deficiencies, it is important to be careful with the recommendation of high-concentrated medications, because according to the Arndt-Schultz law, high-concentrated medicaiton will harm the vital energy even further, leading to increase the internal Heat, that is comprehended as the  inflammatory process in Western Medicine and increasing the risk of having intravascular coagulation, myocardial infarction, renal insuficiency and respiratory insuficiency due to the lack of energy of the chakras tha tis responsible for the proper functioning of these organs. The use of homopathic medications in these patients are very important to replenish the functions in all the chakras’ energies centers that are responsible for the production of Yin, Yang, Qi and Blood of the patients, and replenish the second chakra, that is reponsible for the Zheng-Qi, that is the force respomsible for the protection of the body against the invasion of exetrnal pathogenic factor, in this case, SARS-CoV-2 infection.

Meetings International -  Conference Keynote Speaker  Alexandre Ehrhardt photo

Alexandre Ehrhardt

Medical Laboratory Scientist, Brazil

Title: Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Biography:

Alexandre Ehrhardt is an Adjunct Professor  with a demonstrated history of working in Clinical Laboratory. Skilled in Toxicology and Pharmacology, Immunology and Hematology. Hold a strong professional education with a Master Degree in Pharmacology and Therapeutics focused in Development of Bioactives Compounds from Universidade Federal do Rio Grande do Sul (Brasil). Currently is developing a project focusing on Biomaterials with antibacterial and antifungal activity.

Abstract:

A plethora of bacteria and fungi are able to alternate planktonic growth and community growth, commonly referred as biofilms. Orthodontic appliances favors the colonization by Candida albicans yeasts (C. tropicalis, C. parapsilosis and C. krusei) in the saliva of individuals with or without clinical manifestations of candidiasis. The concern of biofilm formation during orthodontic treatment, associated with dental plaque formation and periodontal diseases is of concern considering that Candida spp. biofilms have a great resistance to antifungal drugs according to several studies. In order to minimize this problem, it is proposed to add antifungal properties to a biomaterial by modifying a glass ionomer cement with the addition of an imidazolium salt: C16MImCl. The process consisted of an structural modification of a commercially available glass ionomer cement by inserting the imidazolium salt 1-n-hexadecyl-3-methylimidazolium chloride (C16MImCl), generating a new biomaterial with antifungal biofilm activity. Test specimens were prepared using a commercial glass ionomer cement to which 10 ppm of cetylpyridinium chloride (CPC) as a reference ionic antifungal agent and C16MImCl were added. The feasibility and hypoallergenicity of the new biomaterial were assessed by microhardness plastic deformation and chorioallantoic membrane assays. Colony counting and SEM images evaluated the modified specimens’ antibiofilm activity against three multidrug-resistant Candida species. The modified glass ionomer cement presented a strong antibiofilm activity against Candida spp., without losing its original micromechanical and hypoallergenic properties. A good biofilm penetration was observed, breaking the fungal protection and characterizing an antifungal effect even at very low concentrations.

Besides that, the CPC and  C16MImCl incorporation into the glass powder and subsequent polymerization reaction did not modify the microhardness of the TS. This initial step is of utmost importance, since the inclusion of additives can compromise the physical–mechanical properties of GIC.  Considering the demand for biomaterials with antibiofilm activity, this new biomaterial could potentially improve the classical ionomer cement applicable in many areas of dentistry.