Be a part of 5^th International Conference on Biosensors and Bioelectronics

Title: Electrochemical aptamer-based (EAB) sensors: a platform technology supporting real-time molecular monitoring in the living body

Biography:

Current methods for monitoring specific molecules in the living body, such as the continuous glucose monitor, rely on the enzymatic or chemical reactivity of their targets, and thus are not generalizable to new targets. For this reason, only a handful of metabolites and neurotransmitters can currently be measured in vivo. Against this background, we are developing a molecular measurement platform that: (1) has been demonstrated able to work in the living body and (2) is independent of the reactivity of its targets and thus is general

Abstract:

Robert Batchelor completed both his MS in Pharmacology and BS in Biochemistry at the University of Washington in Seattle, USA. Since then, he has gained over twenty years’ experience in the biotech industry and has launched over 50 products to market at several companies, including ThermoFisher. He is an expert on developing electrochemical aptamer-based sensors based on his experience at four startup companies in the US and Australia, including Base Pair Biotechnologies in Houston, Texas, and former wearable medicine sensing industry leader Eccrine Systems in Cincinnati, Ohio. He is currently the Head of Biosensors at Nutromics in Melbourne, Australia

Title: Compo-SiL® skin substrates as a biocompatible, sustainable and flexible platform for Biosensors

Biography:

Dr. Anupam Mukherjee has a multidisciplinary background of achievements in synthetic organic chemistry, material science for optoelectronic applications and silicone materials & technology and its production and diverse applications. Currently, in General Silicones as Technical Director of R&D Center, he is engaged in corporate entrepreneurship to develop new ideas and opportunities within established business and carrying out investigations on design and development of various innovative large-scale manufacturing of high value- added silicone products following multi manufacturing processes

Abstract:

Title: High Coverage Inductive Interface for Implants in Small Animals

Biography:

Ana Domingues has completed his Mater at the age of 23 years from University of Minho (Portugal), in Erasmus context in University of Freiburg (Germany). She worked almost one and half years as Biomedical Engineer. Currently, she is Project Engineer at Active Space Tecnologies in Coimbra, Portugal

Abstract:

In Biomedical Engineering, inductive wireless power transfer (IWPT) has been investigated by many researchers to charge active implantable medical devices (AIMDs) since IWPT is safe and avoids the implementation of cables, preventing infections through the skin and movement limitations. This research develops a high coverage inductive interface to build a cage that works as a tool to acquire and study the neuronal activity in small animals. The coverage is constituted by big transmitter coils in order to charge homogeneously implants in free-moving small animals, where the receiver coil is fully implanted. Different approaches, as the implementation of bigger coils, segmentation technique, multicoil array were combined to maximize the covered area and optimize the power distribution homogeneity as well as the power transfer efficiency.

Title: Biosensors and Bioelectronics: Current Trends to Future Applications

Biography:

Dr Yuvaraja Visagathilagar has over 26+ years of extensive expertise and experience in academia, research and industry. He graduated with Bachelor of Engineering in Communication Engineering and Doctorate in Engineering (with a highly prestigious scholarship from the Australian Government) in 1996 and 2003 respectively from RMIT University, Melbourne Australia. His dissertation was in “Narrow-band Optical Modulator on Lithium Niobate” for telecommunication applications but it can be applied for other transceivers applications.

Abstract:

For many decades, sensing has been a key global application for many commercial and defence applications [1]. Early sensing technologies has been using either electrical (or RF/Microwave) technologies however, in recent global research and development has focused on smart optical sensing technologies. Predominantly these technologies provide: (a) compact and robust (b) immunity to electromagnetic interference; (c) use of low cost telecommunication fibre cables; (d) long distance; and (e) not susceptible to harsh environment [1, 2] (f) ease of manufacture and other factors. The optical sensing technologies have been applied for leak detection, vibration/perimeter detection and health monitoring due to its high sensitivity and localisation with sub-metre spatial resolution. In traditional optical sensing technologies have been used in monitoring of large-scale perimeter and pipeline monitoring [3] due to the cost of the technology.

Title: Discrimination of red blood cells of different pathological states by statistical analysis of physical parameters, obtained with biosensing technology during microcirculatory

Biography:

Bruno Le Pioufle, PhD from University Paris XI, is Professor at ENS Paris-Saclay, within the University Paris-Saclay. He is the Director of Institut d’Alembert. He is author of more than 70 papers in scientific journals

Abstract:

Red blood cell (RBC) genetic disorders affect millions of peoples in the world. Abnormal hemoglobin (HbS) is produced and fills the denuclearized RBC. Under hypoxic condition, HbS polymerizes and RBC with a diameter of 8µm loses its elasticity and deformability to pass through the blood microcapillaries network. Such disorder can be found for example in Sickle Cell Disease (SCD), and might induce vaso-occlusive and organs dysfunction. For the abnormal RBCs detection, bioimpedance measurement of cells injected into a microfluidic device is proposed. Electrically monitoring the transit of RBC in the microfluidic network, comprising fluidic restrictions, the RBCs of different pathological states can be discriminated. The device was made in Polydimethylsiloxane (PDMS) casted thanks to soft lithography technology.

Title: Carbon quantum dots and Acetylcholinesterase- based fluorescent biosensor for pesticide detection in waters

Biography:

Maria Isabel Gaviria Arroyave, currently Ph.D. (c) in Environmental Engineering at Universidad de Antioquia and CEO of Taxia mentoring start-up. Degree in Biological Engineering from Universidad nacional de Colombia and Master in Engineering from Universidad de Antioquia. Up to 10 years of experience in innovation and development processes, applying cutting-edge technologies like environmental biotechnology and green nanotechnology. Previous positions in R&D manager at Universidad EIA and Biotechnology chief in SENA. Senior consultant in innovation and circular economy for Taxia mentoring and Distilled innovation. National doctoral fellowship from Minciencias (2018-present) and Swiss government fellowship from University of St.Gallen (AIT program 2020-2021).

Abstract:

Water sources in rural areas are exposed to harmful Organophosphorus pesticides (OP) that should be detected before human consumption [1], and biosensors have emerged as an alternative [2]. The application of nanomaterials, including carbon quantum dots (CD), can significantly improve the performance of optical biosensors. In this work, naturally fluorescent and non-toxic CD synthesized previously [3]from African-oil palm biochar were integrated with Acetylcholinesterase enzyme (AChE) as a bioreceptor, to produce a fluorescent biosensor. This system is modulated with graphene oxide (OG), showing a fluorescence recovery in the presence of the OP. The biosensor was evaluated under pure chlorpyrifos, but also under a commercial formulation called Lorsban®. We obtained a limit of detection (LOD) as low as 0.13 ppb and 2.14 ppb for chlorpyrifos and Lorsban® respectively. The system also shows a good selectivity against proteins and other organic substances usually present in drinking water, even in tests with tap water.

Title: Agro-industrial African oil palm residue reuse for the development of an optical biosensor based on Carbon dots for BSA detection

Biography:

Juan Pablo Arango is currently a Researcher in the GIBEC research group at EIA University in Colombia. Prior to his recent position, he was a visiting scholar in the department of Physiology at the University of Kentucky. He received his bachelor’s in biomedical engineering from EIA University in December 2018 and is currently finishing his master’s in biomedical engineering also from EIA University. He is currently the director of the Technologies for the detection of biomolecules hotbed of research in EIA University, where he hopes to involve and train undergraduate students in the research process

Abstract:

The present study developed an optical biosensor based on Carbon Dots (CDots) obtained from Elaeis guineensis biochar, for the detection of a model molecule, in this case, Bovine albumin serum (BSA). The CDots had a size of 2.5 ± 0.7 nm determined through a High-Resolution Transmission Electronical Microscopy (HR-TEM), a Z potential of -56.1 ± 2.37 mV and a Quantum yield of 1.69%, with emission and excitation wavelengths of 428 and 320 nm, respectively. As a bioreceptor molecule, the anti-BSA was used and conjugated to the CDots surface using the carbodiimide method. The fluorescence of the CDots was evaluated through a fluorescence spectroscopy and posteriorly modulated using graphene oxide. Finally, the performance of the biosensor was analysed by evaluating the specificity and sensitivity, where a qualitative biosensor was obtained that detects in a range of 1000 - 10 mg / µL of BSA. With the implementation of this technology, it will contribute to the improvement of the quality of life of Colombian vulnerable populations while contributing to the closing of cycles of the oil palm industry.

Title: Challenge to meet the market need for faster diagnosis in health care: an interdisciplinary approach to biosensors

Biography:

Laure Abensur Vuillaume is emergency physician (M.D) and has completed his PhD in biological science from Lorraine University (France). She works and develops expertise in applied health technologies and medical education

Abstract:

To improve the efficiency of current medical practices, more significant data from technology is needed. One lever to optimize medical decision time is to shorten the delay from biological test to results. In the field of fast biological tests, biosensors have received increasing attention and several technologies have been developed to deliver portable, cheap and sensitive analytical systems(1,2). Nevertheless, two main obstacles prevent the marketing of these biosensors: 1) an accurate analysis of the market in terms of real needs for medical practices and 2) perfect matching with current medical recommendations