April 25-26, 2022 | 11:30 AM GMT


Las Vegas, USA

Conference Agenda

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Keynote Session:

Meetings International -  Conference Keynote Speaker Fadi Ibrahim photo

Fadi Ibrahim

Department of Chemistry, Saad Bin-Alrabee Alansari School Kuwait.

Title: Nanoparticles and Quercetin Synergize with NIR Laser for Covid-19 Infectious Diseases Treatment


The winner of PhD graduate research award in applied sciences for postgraduate research project from Kuwait University 2013/2014. Participated in the “International Conference on Chemistry and Chemical Engineering” (ICCCE-2015) September 14-16, 2015, Dubai- United Arab Emirates.Participated in the 2nd Kuwait Oil & Gas Show and Conference 2015.The winner of Kuwait National Petroleum Company KNPC-8th CEO Annual HSE improvement performance, 2015.The winner of best paper award certificate from TJPRC “International Journal of Nanotechnology and Application”, 2015, with paper titled “Synthesis of Smectic and Discotic Liquid Crystals Derivatives by Flow Injection System”.The winner of Energy Globe National Award 2016 "Polymer for Climate Protection".Participated in 27th International Conference on Organometallic Chemistry


This work shows that novel virus-like mesopore silica-zinc oxide/Ag nanoparticles (SZnOAg) synthesized and professionally collected on NIR laser irradiation with quercetin to improve their effectively eliminates the virus as a biomedical application. The properties of the nanoparticles can be tuned with respect to their core diameter, tubular length, and outer diameter. Due to their biomimetic appearance, they can rapidly transform living cells into virus-like particles, this SZnOAg nanomaterials has specific elimination effect on bacteriophage and covid-19. Using epitaxial growth, we can construct virus-like structures that can be used for biomedicine applications. These nanomaterials and NIR laser could open the way to a new range of antiviral materials, due to the low-efficiency cellular uptake of current nanoparticles, their applications in the biomedical field are limited. Herein, it clearly shown that novel mesoporous silica nanoparticles can be easily exhibited superior cellular uptake property.

Meetings International -  Conference Keynote Speaker S J Parmer photo

S J Parmer

Department of Pharmaceutical Sciences, Sardar Patel University, India

Title: Formulation and evaluation of Microemulsion based gel of dimethyl fumarate for Psoriasis as topical delivery


Shraddha Parmar has completed her PhD at the age of 31 years from Sardar Patel University, the State University of Gujarat, India. She has been working as Assistant Professor at Department of Pharmaceutical Sciences, Sardar Patel University, State University of Gujarat, India for the past 9 years. She has published more than 35 papers in reputed international journals and presented two papers in international conferences. She has guided 20 Masters Studentsfortheirdissertationwork.


The rationale of the current investigation was to develop a microemulsion based gel in the treatment of Psoriasis. The study consisted of Preformulation studies, Analytical method development studies, Formulation and characterization studies, Drug release studies and stability study. On the basis of results of solubility studies in different oils, surfactants and co-surfactants, tween 20 used as surfactant, IPA as co-surfactant and limonene as oil were chosen for the study. Pseudo ternary phase diagrams in different ratios of oils, S mix and water were developed, and 3:1 is suitable for preparation of MBG. On the basis of transparency, centrifugation, pH, globule size, zeta potential, polydispersity index, conductivity, thermodynamic stability, TEM, Dye solubility test and dilution test, formulation ME 2 batch was selected as an optimized formulation for designing Microemulsion. The pH of the formulations was found to vary between 6.26 and 6.79, a near neutral range which is ideal for topical applications. The Transmission electron microscopy of dimethyl fumarate loaded microemulsion showed a nanosized (70.31 nm) and spherical shape. The optimized batch has (-11.1) mV zeta potential, which indicates stable Microemulsion. From the stability study, we conclude that none of the Microemulsion systems showed signs of phase separation on centrifugation and freeze thaw cycle, so we conclude that the optimized batch was robust enough. The optimised ME 2 batch of dimethyl fumarate microemulsion was further incorporated in gel using aloe vera as moisturizing agent, carbopol as gelling agent. The pH of MBG was acceptable for the topical delivery system.

Meetings International -  Conference Keynote Speaker Jigar A. Shah  photo

Jigar A. Shah

Manager (Analytical Development), Baroque Pharmaceutical Pvt Ltd, Vaghasi, Dist.- Anand (Gujarat) India -388320



Jigar Shah is the Director for the Loan Program Office at the U.S. Department of Energy. In his role, Shah leads and directs the Loan program Office focused on building a bridge to commercial financing for technologies that are ready to scale the transition to a global clean energy economy. He oversees the planning and execution of the organization’s over $40B of authority within manufacturing, innovative project finance, andtribalenergy.


In recent time Club is become a main place of crimes like rape, murder, robbery, etc in metro cities. These types of social crimes are done mostly by using the newly invented medicines. Club crimes are type of assaults where the victim and the offender are in, or have been in, some form of personal social relationship, ranging from a first get together to an established relationship. Club drugs can incapacitate a person for a period of time and cause memory loss. These drugs may be colorless and odorless; their taste is easily masked. They may be in liquid form or dissolve easily in liquid. After ingestion, effects can occur immediately or within 15 to 30 minutes. The drugs described here are often called “date rape drugs” because they quickly increase a person’s vulnerability to sexual assault

Meetings International -  Conference Keynote Speaker Eman R. Esharkawy  photo

Eman R. Esharkawy

Department of Chemistry, College of Science, Northern Border University, Arar, Saudi Arabia

Title: In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa.


chemistryFaculty of Science, Northern border universityResearcher in Desert research center


Inflammation, oxidation, and compromised immunity all increase the dangers of COVID-19, whereas many pharmaceutical protocols may lead to increased immunity such as ingesting from sources containing vitamin E and zinc. A global search for natural remedies to fight COVID-19 has emerged, to assist in the treatment of this infamous coronavirus. Nigella satvia is a world-renowned plant, an esteemed herbal remedy, which can be used as a liquid medicine to increase immunity while decreasing the dangers of acute respiratory distress syndrome. Thymoqinone (TQ), dithymoqinone (DTQ) and thymohydroquinone (THQ), are major compounds of the essential oil contained in N. sativa. A current study aims to discover the antiviral activity of two compounds, Thymohydroquinone and Dithymoquinone, which are synthesized through simple chemical procedures, deriving from thymoquinone, which happens to be a major compound of Nigella sativa. A half-maximal cytotoxic con-centration, “CC50”, was calculated by MTT assay for each individual drug, The sample showed anti-SARS-CoV-2 activity at non-cytotoxic nanomolar concentrations in vitro with a low selectivity index (CC50/IC50 = 31.74/23.15 = 1.4), whereby Dimthymoquinone shows high cytotoxicity.

Meetings International -  Conference Keynote Speaker Charmy Kothari photo

Charmy Kothari

Department of Pharmaceutical Analysis, Institute of Pharmacy, Nirma University, Gujarat, India

Title: A rapid and sensitive HPLC method for simultaneous determination of Rosuvastatin and Candesartan in human plasma: A useful tool for pharmacokinetic studies


Dr. Charmy S. Kothari has 18 years of teaching and research experience. Her research areas of interest are analytical and bioanalytical method development and validation, impurity profiling and stability studies as well as Isolation, identification and characterization of marker compounds from plants and formulations. Her research area also includes regulatory guidelines, registration procedures, evaluation and approval procedures of various regulatory agencies worldwide as well as Pharmacovigilance system. She has more than 50 research and review papers published in reputed Indian and International journals.


A rapid and sensitive high-performance liquid chromatography (HPLC) method was developed and validated in human plasma for simultaneous determination of rosuvastatin and candesartan, using atorvastatin as internal standard. Chromatographic separation was achieved on a Waters C18 column (250 × 4.6 mm, 5 µm). A response surface methodology based 3 2 full factorial design was employed to optimize critical chromatographic conditions viz. pH and composition of mobile phase for achieving good resolution between the desired analytes.

Keynote Session:

Meetings International -  Conference Keynote Speaker Panneerselvam Theivendren photo

Panneerselvam Theivendren

Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Elayampalayam-637205, Namakkal, Tamil Nadu, India

Title: Graph Theoretical analysis and in silico modeling and molecular dynamic studies of thiazole derivatives for the modulation of glucose metabolism in 3T3-L1 adipocytes


Dr. T. Panneerselvam working as a Professor cum Director R&D, Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy. He has 15 years of teaching and research experience with the credential of 24 patents, 01 textbook 21 research books and 85 scientific research articles with impact in international and national journals


Adipocytes was investigated in the following study. The thiazole and its derivatives were found to have a wide range of biological actions, including anti-diabetic efficacy. Various spectral analyzers were used to assess the synthesized analogs, and the findings of the characterizations were used to corroborate the properties of the synthesized analogs.Methodology: The mechanism underpinning that the glucose utilisation of thiazole derivatives was investigated using molecular docking with the chosen target, and in silico studies revealed a robust interaction between thiazole derivatives and AMPK binding sites. The synthesized thiazole analogs were tested for their in vitro cellular viability and glucose uptake on 3T3-L1 adipocytes based on the significant report of in silico screening.

Meetings International -  Conference Keynote Speaker Julien Orts photo

Julien Orts

University of Vienna, Division of Pharmaceutical Chemistry, Austria

Title: Lead Generation without an X-Ray Crystal Structure: An NMR Method to Probe Protein-Ligand Complexes


Julien Orts studied Physics and Biophysics and graduated in 2010 jointly from the Max Planck Institute for Biophysical Chemistry and the European Molecular Biology Laboratory under the guidance of Prof. Carlogmano and Prof. Griesinger. Julien joined the BioNMR laboratory at the ETH Zurich led by Prof. Riek, first as a post-doc and then as a junior group leader. Since 2021 he is an Assistant Professor at the University of Vienna in the Division of Pharmaceutical Chemistry.


X-ray crystallography molecular replacement (MR) is a highly versatile tool for the detailed characterization of lead compound and binding modes in the pharmaceutical industry. The two major limitations of its application to drug research are (i) the availability of a similar protein structure, and (ii) obtaining well-diffracting crystals of the ligand-protein complexes of interest. While nowadays the first point is often not a limitation anymore, obtaining well-diffracting crystals might be difficult. In such situations structure determination of protein-ligand complexes by liquid-state NMR is a good option. Unfortunately, the established standard structure determination protocol is in general time-consuming, and a shortcut using available structural data as in the case of MR in X-ray crystallography is not available.Here, we present NMR2(NMR Molecular Replacement), a MR-like approach in NMR to determine the structures of the binding pockets of ligands at atomic resolution. The calculation of structures of protein-ligand complexes relies on the collection of unassigned semi-quantitative inter-molecular NOE distance restraints and on previously solved structures.[

Meetings International -  Conference Keynote Speaker Matthias O. Agbo photo

Matthias O. Agbo

Department of Pharmaceutical and Medicinal Chemistry, University of Nigeria, Nsukka

Title: Discovery and Heterologous Expression of the Large GC-Rich Marinomycin Biosynthetic Gene Cluster


Assoc. Prof. Matthias Agbo is a lecturer in Pharmacy at the University of Nigeria since 2011. His research is in the isolation, characterization and assessment of new medicinally relevant natural products from Nigerian medicinal plants. This includes screening isolated compounds for activity against bacteria


Marinomycins are polyene antibiotic isolated from marine microbe (Marinispora CNQ-140) with high activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREF) known to be the causative organisms for most infectious diseases. In dim light Marinomycin A isomerizes to Marinomycin B and Marinomycin C with lesser potency against MRSA and VREF. Understanding the Marinomycins biogenetic gene cluster (BGC) has been a difficult task due to their large sizes and high GC content which makes the cluster susceptible to re-arrangement. Transformation of Streptomyces lividans by construct containing the cluster and heterologously expressing the encoded biogenetic cluster aided the production of Marinomycins.

Meetings International -  Conference Keynote Speaker Stefania Costa photo

Stefania Costa

Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara, Ferrara, Italy

Title: Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride


Stefania Costa was born in Ferrara, Italy, in 1984. She received his master’s degree in medical-pharmaceutical biotechnology in 2009 from University of Ferrara and obtained his PhD degree in Pharmaceutical Sciences in 2014. University. Since 2010 she has been a research fellow at the Department of Life Sciences and Biotechnology of the University of Ferrara.


Bile acids (BAs) are a family of steroids synthesized from cholesterol in the liver. Among bile acids, ursodeoxycholic acid (UDCA) is the drug of choice for treating primary biliary cirrhosis and dissolving cholesterol gallstones. The clinical effectiveness of UDCA includes its choleretic ac tivity, the capability to inhibit hydrophobic bile acid absorption by the intestine under cholestatic conditions, reducing cholangiocyte injury, stimulation of impaired biliary output, and inhibition of hepatocyte apoptosis. Despite its clinical effectiveness, UDCA is poorly soluble in the gastro-duo deno-jejunal contents, and pharmacological doses of UDCA are not readily soluble in the stomach and intestine, resulting in incomplete absorption. Indeed, the solubility of 20 mg/L greatly limits the bioavailability of UDCA. Since the bioavailability of drug products plays a critical role in the design of oral administration dosages, we investigated the enzymatic esterification of UDCA as a strategy of hydrophilization

Meetings International -  Conference Keynote Speaker BAKYALAKSHMI. M photo


Associate Professor, Department Of Pharmaceutical Chemistr, Sri Vijay Vidyalaya College Of Pharmacy, Dharmapuri, Tamilnadu

Title: Synthesis, Spectrum Characterization And Estimation Of Biological Activity Of New Heterocycylic Compound




This present work deals with the synthesis of new azo derivative based on reaction between Amino pyridine and Para hydroxy benzoic acid. The synthesized compound were determined by spectrum characterization and screened for Antimicrobial and anthelmintic activity.

Meetings International -  Conference Keynote Speaker Sergey Suchkov photo

Sergey Suchkov

Sechenov University, Moscow, Russia

Title: Antibodies (Abs) with Functionality (Ab-Proteases) as a New Generation of Translational Tools designed get Healthcare Model Re-Armed


Sergey Suchkov graduated from Astrakhan State Medical University and awarded with MD, then in 1985 maintained his PhD at the I.M. Sechenov Moscow Medical Academy and in 2001, maintained his Doctorship Degree at the Nat Inst of Immunology, Russia. From 1987 through 1989, he was a senior Researcher, Koltzov Inst of Developmental Biology. From 1989 through 1995, he was a Head of the Lab of Clinical Immunology IKI.


Abs against myelin basic protein/MBP endowing with proteolytic activity) are of great value to monitor demyelination to illustrate the evolution of multiple sclerosis. Anti-MBP autoAbs from MS patients and mice with EAE exhibited specific proteolytic cleavage of MBP which, in turn, markedly differed between: MS patients and healthy controls. different clinical MS courses.  EDSS scales of demyelination to correlate with the disability of MS patients to predict the transformation prior to changes of the clinical course.Ab-mediated proteolysis of MBP was shown to be sequence-specific whilst demonstrating fivesites of preferential proteolysis to be located within the immunodominant regions of MBP and tofall inside into 5 sequences fixed.