webinar on

Stem Cell

May 29, 2021

Stem Cell

Theme: the advances and challenges for the development of stem-cell-based therapies

We welcome all the participants across the planet to attend the webinar on Stem cell during May 29, 2021, includes the theme “The advances and challenges for the development of stem cell based therapies". Stem cells have offered much hope by promising to greatly extend the numbers and range of patients who may benefit from transplants, and to supply cell replacement therapy to treat debilitating diseases like diabetes, Parkinson's and autosomal dominant disease. The difficulty of somatic cell research is politically charged, prompting biologists to start engaging in ethical debates, and generating within the general public an oddly high level of interest during this aspect of biology. But excitement notwithstanding, there's a protracted thanks to get into basic research before new therapies are going to be established, and now the pressure is on for scientists and clinicians to deliver.

1. Stem cell therapy

Stem cells have the power to differentiate into specific cell types. The two defining characteristics of a somatic cell are perpetual self-renewal and also the ability to differentiate into a specialized adult cell type. There are two major classes of stem cells: pluripotent that may become any cell within the frame, and multipotent that is restricted to becoming a more limited population of cells. Cell sources, characteristics, differentiation and therapeutic applications are discussed. Stem cells have great potential in tissue regeneration and repair but much still has to be learned about their biology, manipulation and safety before their full therapeutic potential may be achieved.

2. Hematopoietic stem cell transplantation

Bone marrow transplant also referred to as hematopoietic somatic cell transplant (HPSCT) involves the administration of healthy hematopoietic stem cells to patients with dysfunctional or depleted bone marrow. This helps to reinforce bone marrow function and, looking on the disease being treated, ends up in either destruction of neoplasm cells or to generation of functional cells which will replace the dysfunctional ones, as is that the case of immune-deficiency syndromes, hemoglobinopathies, and other diseases. This activity reviews the indications, contraindications, and complications related to hematopoietic somatic cell transplants and highlight the role of the interprofessional team within the management of patients requiring this treatment.

3. Neurodegenerative diseases

Neurodegenerative disease is an umbrella term for a range of conditions which primarily affect the neurons in the human brain.Neurons are the building blocks of the nervous system which includes the brain and spinal cord. Neurons normally don’t reproduce or replace themselves, so when they become damaged or die they cannot be replaced by the body. Examples of neurodegenerative diseases include Parkinson’s, Alzheimer’s, and Huntington’s disease.Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and / or death of nerve cells. This causes problems with movement (called ataxias), or mental functioning (called dementias).Dementias are responsible for the greatest burden of neurodegenerative diseases, with Alzheimer’s representing approximately 60-70% of dementia cases.

4. Somatic cell nuclear transfer

In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking an enucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell. It is used in both therapeutic and reproductive cloning. "Therapeutic cloning" refers to the potential use of SCNT in regenerative medicine; this approach has been championed as an answer to the many issues concerning embryonic stem cells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types truly are.

5. Regenerative treatment

Regenerative medicine seeks to replace tissue or organs that are damaged by disease, trauma, or congenital issues, vs. this clinical strategy that focuses totally on treating the symptoms. The tools wont to realize these outcomes are tissue engineering, cellular therapies, and medical devices and artificial organs.
Combinations of those approaches can amplify our natural healing process within the places its needed most, or take over the function of a permanently damaged organ. Regenerative medicine could be a relatively new field that brings together experts in biology, chemistry, technology, engineering, genetics, medicine, robotics, and other fields to seek out solutions to a number of the foremost challenging medical problems faced by humankind.

6. Drug discovery and biomedical research

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Modern drug discovery involves the identification of screening hits,medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability. Once a compound that fulfills all of these requirements has been identified, the process of drug development can continue. If successful, clinical trials are developed. Biomedical research is the broad area of science that involves the investigation of the biological process and the causes of disease through careful experimentation, observation, laboratory work, analysis, and testing.

  • stem cell therapy
  • hematopoietic stem cell transplantation
  • neurodegenerative diseases
  • somatic cell nuclear transfer
  • Regenerative treatment
  • Drug discovery and biomedical research

4 Renowned Speakers

Peter Everts

Gulf Coast Biologics, USA
United States of America

Masahiro Onuma

Trisguid Ltd, Japan
Japan

TALHA BIN EMRAN

BGC Trust University, Bangladesh
Bangladesh

Baljeet singh

Lovely Professional University, India
India