A defect in a single gene causes Huntington’s disease. It’s considered an autosomal dominant disorder. This means that one copy of the abnormal gene is enough to cause the disease. If one of your parents has this genetic defect, you have a 50 percent chance of inheriting it. You can also pass it on to your children.
The genetic mutation responsible for Huntington’s disease is different from many other mutations. There isn’t a substitution or a missing section in the gene. Instead, there is a copying error. An area within the gene is copied too many times. The number of repeated copies tends to increase with each generation.
Dementia is the term applied to a group of symptoms that negatively impact memory, but Alzheimer’s is a progressive disease of the brain that slowly causes impairment in memory and cognitive function. The exact cause is unknown and no cure is available.
The National Institute of Health estimates that more than 5 million people in the United States have Alzheimer’s disease. Although younger people can and do get Alzheimer’s, the symptoms generally begin after age 60.
The time from diagnosis to death can be as little as three years in people over 80 years old. However, it can be much longer for younger people.
Parkinson-type motor skills problems (e.g. slowness, stiffness, tremors) are also common in people with dementia with Lewy Bodies (LBD) and are often present at the time of diagnosis.
Semantic dementia refers to a progressive loss of the ability to remember the meaning of words, faces and objects, which results from shrinkage of the temporal lobes of the brain. However, there is wide variation in the speed of progression. Some people show little decline over the course of a year whereas others change more quickly. Usually, monitoring a person’s progress over a year will give a good guide as to the likely future rate of progression.
The early stage of Frontotemporal dementia has different symptoms as memory and cognitive functioning are relatively spared. Behavioral variant frontotemporal dementia (bvFTD) primarily influences individuals’ behaviors and emotions. Common behavioral changes include becoming uncharacteristically selfish, apathetic, and uninhibited. Over-eating can also be a problem.
Individuals with bvFTD might act impulsively and inappropriately in social situations, disregarding manners. There are two other less common forms of frontotemporal dementia with different initial symptoms. Semantic dementia primarily affects the ability to recall names and understand language, and progressive non-fluent aphasia affects individuals’ abilities to produce fluent speech.
People with vascular dementia have distinct mental element shortfalls that incorporate each reminiscence hindrance, that impacts the adaptability to find out new statistics or review facts already learned, and one or greater of the ensuing aspect outcomes aphasia, apraxia, agonise, or reputable brokenness to such an extent that the mental detail shortages adversely affect social or action working with a chief decrease in beyond abilities. Furthermore, human beings with dementia commonly enjoy the ill consequences of comorbid situations that more confuse thoughts and block best results.
In some cases, treating the condition that causes dementia may help. Conditions most likely to respond to treatment include dementia due to:
• metabolic disorders
In most cases, dementia isn’t reversible. However, many forms are treatable. The right medication can help manage dementia. Treatments for dementia will depend on the cause.
Bioinformatics advent can be used to regulate and evaluate data from the current high-throughput research technologies and render means for novel discoveries in the field of neurodegenerative diseases. It is reported that there is very little published data on epigenomics. It is said that the data are obtained from high throughput technologies in the screening of the human brain. These data intend the upcoming researchers to know and design their experiments. Data Mining plays an important role in the prediction of the disorder, where the actual data is compared with the real data and the results are interpreted. The Transcriptomics and Proteomics studies have also been carried out providing necessary solutions for the problems.
Caring for a person with dementia influences distinctive people in diverse ways. In any case, caring can also be both physically and rationally debilitating. It affects all factors of your life and may have an impact on you to feel separated, driven, and in instances even discouraged. You may additionally have your own physical and psychological well-being needs, which you and others may additionally neglect while you are tending to some other person. There are severe high-quality things about caring.
Early-stage vascular dementia slightly resembles Alzheimer’s, although instead of being primarily characterized by forgetfulness, it is more associated with difficulty planning, decision-making, and following steps. Other early symptoms include slower speed of thought, difficulty maintaining focus, and increased likelihood of experiencing anxiety, depression, and mood swings. Following one or more strokes, Vascular dementia may also include physical symptoms such as vision or speech problems and weakness in limbs, although these symptoms might show improvement with rehabilitation.
Mild cognitive impairment (MCI) is a condition in which someone has minor problems with cognition - their mental abilities such as memory or thinking. In MCI these difficulties are worse than would normally be expected for a healthy person of their age. However, the symptoms are not severe enough to interfere significantly with daily life, and so are not defined as dementia.
It is estimated that between 5 and 20% of people aged over 65 have MCI. It is not a type of dementia, but a person with MCI is more likely to go on to develop dementia. This page explains what MCI is, the link between MCI and dementia, and the benefits of diagnosing MCI. It then looks at treatments for MCI, ways to cope with the symptoms, and how you can reduce your risk of developing MCI and dementia. Many people who are diagnosed with MCI use this as an opportunity to change their lifestyle for the better. There is a lot that someone can do to help reduce their chances of MCI progressing to dementia.
Lewy body dementia can also look a little like Alzheimer’s in the early stage, although there are some key differences. In the early stage of Dementia with Lewy bodies (LBD), the individual’s attention and awareness can fluctuate greatly from day to day, or even from moment to moment. Many also have recurrent visual hallucinations that they are able to describe in vivid detail, and some have auditory hallucinations as well. Sometimes these can lead to faulty perceptions and delusions of persecution.